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Supernatant 1.0 ml
Concentrate 0.1 ml
Frozen Cells 1 vial
Growing Cells 1 vial
DSHB Data Sheet
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Antigen: Lim 1+2 / LhxV5
Hybridoma Cells Available: Yes
Antigen Species: Rat
Depositor: Jessell, T.M. / Brenner-Morton, S.
Antigen Sequence:
Depositors Institution: HHMI/Columbia University
Antigen Molecular Weight: Predicted: 44.8 kDa
Human Protein Atlas:
Link
Positive Tested Species Reactivity: Chicken, Fish, Human, Mouse, Rat, Zebrafish
Depositors Notes:
Gene: Lhx1
Immunogen: Lim2/LhxV5 (rat); recombinant.
Alternate Gene Names: LIM homeobox 1
Immunogen Sequence: 1-360 aa
Isotype: MIgG1
Alternate Antibody Name: LIM/homeobox protein Lhx1, rlim, LIM homeobox protein 1, homeobox protein Lim-1
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: No
Myeloma Strain: NS-1
Epitope Location or Sequence:
Uniprot ID:
Host Species: mouse
Entrez Gene ID:
Additional Characterization:
Link
Antibody Registry ID:
AB_531784
Additional Information:
Recommended Applications: FFPE, Immunofluorescence, Immunohistochemistry, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
4F2 was deposited to the DSHB by Jessell, T.M. / Brenner-Morton, S. (DSHB Hybridoma Product 4F2)
All cell products contain the antimicrobial ProClin. See our FAQ section for additional information.
Basic fibroblast growth factor reduces functional and structural damage in chronic kidney disease. Villanueva S, Contreras F, Tapia A, Carreño JE, Vergara C, Ewertz E, Cespedes C, Irarrazabal C, Sandoval M, Velarde V, Vio CP American journal of physiology. Renal physiology 2014 Feb 15
Generation of the podocyte and tubular components of an amniote kidney: timing of specification and a role for Wnt signaling. Grinstein M, Yelin R, Herzlinger D, Schultheiss TM Development (Cambridge, England) 2013 Nov
Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells. Christou YA, Ohyama K, Placzek M, Monk PN, Shaw PJ BMC neuroscience 2013 Oct 17
Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Kawaue T, Okamoto M, Matsuyo A, Inoue J, Ueda Y, Tomonari S, Noji S, Ohuchi H Biology open 2012 Nov 15
Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina. Wahlin KJ, Hackler L Jr, Adler R, Zack DJ The Journal of comparative neurology 2010 Dec 15
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. Lamar E, Kintner C, Goulding M Development (Cambridge, England) 2001 Apr
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Tsuchida T, Ensini M, Morton SB, Baldassare M, Edlund T, Jessell TM, Pfaff SL Cell 1994 Dec 16
Synthesis and chromatographic properties of selenazolidine-2-carboxylic acid (beta-selenaproline). De Marco C, Cini C, Coccia R, Blarzino C The Italian journal of biochemistry 1979 Mar-Apr
Generation of the podocyte and tubular components of an amniote kidney: timing of specification and a role for Wnt signaling. Grinstein M, Yelin R, Herzlinger D, Schultheiss TM Development (Cambridge, England) 2013 Nov
Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Emerson MM, Cepko CL Developmental biology 2011 Dec 1
In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jul 27
In vivo activation of channelrhodopsin-2 reveals that normal patterns of spontaneous activity are required for motoneuron guidance and maintenance of guidance molecules. Kastanenka KV, Landmesser LT The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 4
Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. Yang M, Cagle MC, Honig MG The Journal of comparative neurology 2010 Jul 15
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. Lamar E, Kintner C, Goulding M Development (Cambridge, England) 2001 Apr
Topical nitroglycerin for ischemic heart disease. Miner JA, Conti R JAMA 1978 May 19
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation. Inder KL, Ruelcke JE, Petelin L, Moon H, Choi E, Rae J, Blumenthal A, Hutmacher D, Saunders NA, Stow JL, Parton RG, Hill MM Journal of extracellular vesicles 2014
Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. Espana A, Clotman F The Journal of comparative neurology 2012 May 1
Generation of the podocyte and tubular components of an amniote kidney: timing of specification and a role for Wnt signaling. Grinstein M, Yelin R, Herzlinger D, Schultheiss TM Development (Cambridge, England) 2013 Nov
Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2. Waite MR, Skaggs K, Kaviany P, Skidmore JM, Causeret F, Martin JF, Martin DM Molecular and cellular neurosciences 2012 Jan
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation. Inder KL, Ruelcke JE, Petelin L, Moon H, Choi E, Rae J, Blumenthal A, Hutmacher D, Saunders NA, Stow JL, Parton RG, Hill MM Journal of extracellular vesicles 2014
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A Development (Cambridge, England) 2014 Jan
Basic fibroblast growth factor reduces functional and structural damage in chronic kidney disease. Villanueva S, Contreras F, Tapia A, Carreño JE, Vergara C, Ewertz E, Cespedes C, Irarrazabal C, Sandoval M, Velarde V, Vio CP American journal of physiology. Renal physiology 2014 Feb 15
Meis1 regulates Foxn4 expression during retinal progenitor cell differentiation. Islam MM, Li Y, Luo H, Xiang M, Cai L Biology open 2013
Generation of the podocyte and tubular components of an amniote kidney: timing of specification and a role for Wnt signaling. Grinstein M, Yelin R, Herzlinger D, Schultheiss TM Development (Cambridge, England) 2013 Nov
Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells. Christou YA, Ohyama K, Placzek M, Monk PN, Shaw PJ BMC neuroscience 2013 Oct 17
Central and peripheral retina arise through distinct developmental paths. Venters SJ, Mikawa T, Hyer J PloS one 2013
Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Kawaue T, Okamoto M, Matsuyo A, Inoue J, Ueda Y, Tomonari S, Noji S, Ohuchi H Biology open 2012 Nov 15
Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube. Galdo M, Gregonis J, Fiore CS, Compagnone NA Frontiers in endocrinology 2012
Catenin-dependent cadherin function drives divisional segregation of spinal motor neurons. Bello SM, Millo H, Rajebhosale M, Price SR The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Jan 11
Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. Espana A, Clotman F The Journal of comparative neurology 2012 May 1
Temporal and spatial expression of CCN3 during retina development. Laurent M, Le Dréau G, Guillonneau X, Lelièvre E, Slembrouck A, Goureau O, Martinerie C, Marx M Developmental neurobiology 2012 Nov
Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Emerson MM, Cepko CL Developmental biology 2011 Dec 1
Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2. Waite MR, Skaggs K, Kaviany P, Skidmore JM, Causeret F, Martin JF, Martin DM Molecular and cellular neurosciences 2012 Jan
In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jul 27
Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects. Fotaki V, Price DJ, Mason JO The Journal of comparative neurology 2011 Jun 15
Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina. Wahlin KJ, Hackler L Jr, Adler R, Zack DJ The Journal of comparative neurology 2010 Dec 15
In vivo activation of channelrhodopsin-2 reveals that normal patterns of spontaneous activity are required for motoneuron guidance and maintenance of guidance molecules. Kastanenka KV, Landmesser LT The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 4
Spatiotemporally restricted regulation of generic motor neuron programs by miR-196-mediated repression of Hoxb8. Asli NS, Kessel M Developmental biology 2010 Aug 15
Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. Yang M, Cagle MC, Honig MG The Journal of comparative neurology 2010 Jul 15
Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Peltopuro P, Kala K, Partanen J Developmental biology 2010 Jul 1
Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Iulianella A, Sharma M, Vanden Heuvel GB, Trainor PA Development (Cambridge, England) 2009 Jul
Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein. Yu T, Fotaki V, Mason JO, Price DJ The Journal of comparative neurology 2009 Feb 10
Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis. Iulianella A, Sharma M, Durnin M, Vanden Heuvel GB, Trainor PA Development (Cambridge, England) 2008 Feb
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE Genes & development 2008 Jan 15
Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons. Ungos JM, Karlstrom RO, Raible DW Development (Cambridge, England) 2003 Nov
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. Lamar E, Kintner C, Goulding M Development (Cambridge, England) 2001 Apr
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Tsuchida T, Ensini M, Morton SB, Baldassare M, Edlund T, Jessell TM, Pfaff SL Cell 1994 Dec 16
Synthesis and chromatographic properties of selenazolidine-2-carboxylic acid (beta-selenaproline). De Marco C, Cini C, Coccia R, Blarzino C The Italian journal of biochemistry 1979 Mar-Apr
Topical nitroglycerin for ischemic heart disease. Miner JA, Conti R JAMA 1978 May 19