Anti-GHR-ext mAb 74.3
Catalog Fields
Clone ID/Product Name: Anti-GHR-ext mAb 74.3
Available to For-Profits: No
Alternate Antibody Name:
Gene Symbol: GHR
Ab Isotype: MIgG1, kappa light chain
Gene Name:
Antibody Registry ID: AB_2943484
Uniprot ID: P19941
Entrez Gene ID: 100009325
Clonality: Monoclonal
Immunogen: GST fusion protein
Clone:
Immunogen Sequence: a.a. 1-246
Myeloma Strain: P3X63-Ag8.653
Epitope Mapped: No
Antigen Name: Growth hormone receptor
Epitope Location or Sequence: a.a. 128-246 subdomain 2
Alternate Antigen Name:
Deposit Date: 8/24/2022
Antigen Molecular Weight: 71.0 kDa
Depositor: Frank, S.J.
Antigen Sequence:
Depositor Institution: University of Alabama at Birmingham
Antigen Species: Rabbit
Depositor Notes: The epitope of this antibody is in extracellular domain 2. This mAb does not recognize mouse or rat GHR.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Bovine, Human, Porcine, Rabbit
Additional Information: This antibody or its Fab antagonize GH signaling in vivo and in vitro. The antibody also blocks inducible GHR metalloproteolyaia and consequent GH binding protein shedding.
Recommended Applications: Function Blocking, Immunofluorescence, Immunoprecipitation