Antibody Name: E1.9
Antigen:neurofilaments, primary sensory and motor neurons
Catalog Fields
Identity
Clone ID / Antibody Name: E1.9
Alternate Antibody Name: —
Antigen Name: neurofilaments, primary sensory and motor neurons
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: —
Entrez Gene ID: —
Antigen Sequence: —
Antigen Species: Mouse
Antigen Mol. Weight: —
Uniprot ID: —
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgM
Myeloma Strain: FOX-NY
Antibody Registry / RRID: AB_531876
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Whole murine cells from the mid- and hindbrain (development stage: E12)
Immunogen Sequence: Full length protein
Epitope Mapped: No
Epitope Location / Seq: —
Clone: —
Additional Info: In the original paper for E1.9 [PMID: 2300585], the immunogen was described as rat E12, but the subsequent paper from the same authors and in the Depositor's notes it was described as mouse E11. The E1.9 epitope is developmentally regulated. E1.9 recognizes a cytoplasmic epitope in the primary sensory and motor neurons during axonal outgrowth, appearing at E8.5 and disappearing by E12 in the mouse when the same cell populations become positive for mAb B10. It stains neural crest-derived sensory neurons (e.g., neurons of dorsal root ganglia) as well as placode-derived sensory neurons (e.g.neurons of cranial nerves VII and VIII). It is not clear which filaments are recognized by this antibody. For this reason we didn't link it to a Uniprot or gene ID. See mAb B10 for a related antibody.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human, Mouse, Rat
Predicted Reactivity: —
Depositor
Depositor Name: W. Gilbert / D. Stainier
Institution: Max Planck Institute for Heart & Lung Research
Deposit Date: October 24, 1990
Depositor Notes: filaments in growing primary sensory and motor neurons
Recommended Applications
IF
Each lab must optimize concentration per application and species. Full usage recommendations →
UniProt DataUniProtNo UniProt ID
▼No UniProt ID is available for this product.