Clone ID / Name: RIM
Anti - RIM, UNC-10
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: MIgG1
Myeloma Strain: P3X63Ag8.653
Antibody Registry / RRID: AB_579790
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Recombinant His6-tagged UNC-10 (aa 1-144) fusion protein
Immunogen Sequence: Partial protein
Epitope Mapped: Yes
Epitope Location / Seq: aa 1-144
Clone: —
Additional Info: The Rab-3-interacting molecule unc-10 (Rim) localizes to the periphery of the active zone in neurons.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: C. elegans
Predicted Reactivity: —
Depositor
Depositor Name: M.L. Nonet / G. Hadwiger
Institution: Washington University Medical School
Deposit Date: June 21, 2006
Depositor Notes: The antibody works poorly in detecting UNC-10 on immunoblots [PMID: 20405020]. Specific to UNC-10 except that some faint staining was observed in the pharynx of unc-10 mutant [md1117]. By immunofluorescence microscopy on whole mount C. elegans fixed with methanol/acetone, staining was restricted to discrete puncta (active zones) in synapse-rich regions of the nervous system including the nerve ring, the ventral nerve cord and the dorsal nerve cord.
Recommended Applications
IF
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