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DSHB Data Sheet Tell a Friend
Antigen: Discs large (Drosophila) Hybridoma Cells Available: Yes
Antigen Species: Drosophila Depositor: Goodman, C.
Antigen Sequence: Depositors Institution: University of California, Berkeley
Antigen Molecular Weight: Predicted: 106.7 kDaHuman Protein Atlas:
Link
Positive Tested Species Reactivity: DrosophilaDepositors Notes:
Gene: dlg1Immunogen: GST-PDZ2-GST fusion protein; recombinant.
Alternate Gene Names: DLG; DLG-A; DLG1; DlgA; DlgS97; Dmel\CG1725;Immunogen Sequence: same as the antigen
Isotype: MIgG1Alternate Antibody Name: discs large 1, isoform L
Clonality: MonoclonalAlternate Antigen Name:
Epitope Mapped: YesMyeloma Strain: P3 x 63 Ag8.653
Epitope Location or Sequence: a.a 439–756Uniprot ID:
Host Species: mouseEntrez Gene ID:
Additional Characterization:
Link
Antibody Registry ID:
AB_528203
Additional Information: Recommended Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
4F3 anti-discs large was deposited to the DSHB by Goodman, C. (DSHB Hybridoma Product 4F3 anti-discs large)
All cell products contain the antimicrobial ProClin. See our FAQ section for additional information.
Subcellular mapping of dendritic activity in optic flow processing neurons.
Stathmin is required for stability of the Drosophila neuromuscular junction.
Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane.
LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junction.
Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia.
Rab3 dynamically controls protein composition at active zones.
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix.
Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane.
External and circadian inputs modulate synaptic protein expression in the visual system of Drosophila melanogaster.
Subcellular mapping of dendritic activity in optic flow processing neurons.
Synaptic abnormalities in a Drosophila model of Alzheimer's disease.
Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila.
Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly.
Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.
Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions.
Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes.
Three Drosophila liprins interact to control synapse formation.
Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia.
glaikit is essential for the formation of epithelial polarity and neuronal development.
Detection and differentiation of picornaviruses in clinical samples following genomic amplification.
External and circadian inputs modulate synaptic protein expression in the visual system of Drosophila melanogaster.
Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release.
Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction.
Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane.
Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution.
DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization.
Gliotactin and Discs large form a protein complex at the tricellular junction of polarized epithelial cells in Drosophila.
External and circadian inputs modulate synaptic protein expression in the visual system of Drosophila melanogaster.
Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardust.
Subcellular mapping of dendritic activity in optic flow processing neurons.
Synaptic abnormalities in a Drosophila model of Alzheimer's disease.
Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila.
Brain tumor regulates neuromuscular synapse growth and endocytosis in Drosophila by suppressing mad expression.
The kinesin-3, unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila.
Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly.
Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.
Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release.
Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions.
Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-β/BMP signaling and orphan nuclear receptors.
Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction.
Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes.
Stathmin is required for stability of the Drosophila neuromuscular junction.
Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K.
Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane.
Neuroligin 2 is required for synapse development and function at the Drosophila neuromuscular junction.
LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junction.
Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution.
Three Drosophila liprins interact to control synapse formation.
Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia.
Involvement of Lgl and Mahjong/VprBP in cell competition.
Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons.
Drosophila twinfilin is required for cell migration and synaptic endocytosis.
DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization.
Rab3 dynamically controls protein composition at active zones.
Gliotactin and Discs large form a protein complex at the tricellular junction of polarized epithelial cells in Drosophila.
glaikit is essential for the formation of epithelial polarity and neuronal development.
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix.
Congenital corneal anaesthesia and the MURCS association: a case report.
Detection and differentiation of picornaviruses in clinical samples following genomic amplification.
