5D3
Catalog Fields
Clone ID/Product Name: 5D3
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: Cdh1
Ab Isotype: MIgG2b
Gene Name:
Entrez Gene ID: 100337618
Clonality: Monoclonal
Immunogen: Purified E-cadherin extracellular domain (100 kDa trypsin fragment ectodomain) from Xenopus A6 kidney cell line.
Clone:
Immunogen Sequence: partial protein
Myeloma Strain: sp-2/0
Epitope Mapped: Yes
Antigen Name: Cadherin, E-
Epitope Location or Sequence: Extracellular domain
Alternate Antigen Name:
Deposit Date: 5/7/1993
Antigen Molecular Weight:
Depositor: Gumbiner, B.M.
Antigen Sequence:
Depositor Institution: University of Virginia
Antigen Species: Xenopus
Depositor Notes: Blocks epithelial cell-cell adhesion and cell junction formation. Stains ectoderm, all epithelia and regions of cell-cell contact. E-cadherin-specific by immunoblotting and immunoprecipitation.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Drosophila, Xenopus
Additional Information: 5D3 binds both the - and + (Ca++) conformations of E-cadherin
Recommended Applications: FFPE, Function Blocking, Immunofluorescence, Immunoprecipitation, Western Blot