RT97
Catalog Fields
Clone ID/Product Name: RT97
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: NEFH
Ab Isotype: MIgG1
Gene Name:
Entrez Gene ID: 417020
Clonality: Monoclonal
Immunogen: Semi-purified neurofilaments from rat brain homogenate.
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: X63.Ag8.653
Epitope Mapped: Yes
Antigen Name: neurofilament (NF-H)
Epitope Location or Sequence: Phospho-epitopes on the tail domain of neurofilament heavy (and to a lesser extent, neurofilament medium) at KSPXK or KSPXXXK motifs.
Alternate Antigen Name:
Deposit Date: 7/30/1987
Antigen Molecular Weight: Predicted: 112 kDa; Apparent: 200 kDa
Depositor: Wood, J.
Antigen Sequence:
Depositor Institution: Sandoz Institute for Medical Research
Antigen Species: Rat
Depositor Notes: The antibody strongly recognizes polyphosphorylated epitopes on neurofilaments (and to a much lesser extent, on other molecules, e. g. rhodopsin and histones).
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Bovine, Chicken, Human, Mouse, Rat
Additional Information: RT97 reacts with neurofibrillary tangles and plaques [PMID 6178036]. RT97 cross-reacts with neurofilament medium. RT97 has been used as a cell marker for neurons.
Recommended Applications: FACS, Immunofluorescence, Immunohistochemistry, Western Blot