Antibody Name: 2A1
Antigen:Cubitus interruptus (Ci) full length
Immunofluorescent (IF) image of Drosophila wing discs labeled with DSHB antibodies 2A1 against Cubitus interruptus, Ci (blue) and Smoothened (20C6) (red). PMID: 39402333, Fig. EV3C.
Catalog Fields
Identity
Clone ID / Antibody Name: 2A1
Alternate Antibody Name: —
Antigen Name: Cubitus interruptus (Ci) full length
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: CI
Entrez Gene ID: 43767
Antigen Sequence: —
Antigen Species: Drosophila
Antigen Mol. Weight: Predicted: 155 kDa Apparent:180 kDa,
Uniprot ID: P19538
Human Protein Atlas: —
Antibody Properties
Host Species: Rat
Clonality: Monoclonal
Isotype: Rat IgG2a
Myeloma Strain: NSO-1
Antibody Registry / RRID: AB_2109711
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Drosophila protein expressed in E. coli and isolated from inclusion bodies.
Immunogen Sequence: —
Epitope Mapped: Yes
Epitope Location / Seq: a.a. 700-850 at the C-terminus of the Zn finger domain
Clone: —
Additional Info: Has a dual function as a transcriptional activator and a repressor of the hedgehog (Hh) pathway. The full-length ci form (ciFL), acts as an activator (ciA) while ciR, its C-terminally truncated form, acts as a repressor. Involved in segment polarity. Required for the normal development of the posterior half of each embryonic segment.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Drosophila
Predicted Reactivity: —
Depositor
Depositor Name: R. Holmgren
Institution: Northwestern University
Deposit Date: September 27, 2009
Depositor Notes: —
Recommended Applications
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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