10E5
Catalog Fields
Clone ID/Product Name: 10E5
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: ITGA2B
Ab Isotype: MIgG2a
Gene Name:
Antibody Registry ID: AB_2617389
Uniprot ID: P17301
Entrez Gene ID: 3674
Clonality: Monoclonal
Immunogen: Human platelets
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: X63-Ag8.653
Epitope Mapped: Yes
Antigen Name: integrin alpha IIb
Epitope Location or Sequence: alpha IIb cap subdomain
Alternate Antigen Name:
Deposit Date: 3/3/2012
Antigen Molecular Weight: Predicted: 103, 110, and 113 kDa; Apparent: 140 kDa
Depositor: Coller, B.S.
Antigen Sequence:
Depositor Institution: Rockefeller University, Laboratory of Blood and Vascular Biology
Antigen Species: human
Depositor Notes: Inhibits ligand (fibrinogen-von Willebrand factor) binding to integrin alphaIIbbeta3 and platelet aggregation; does not react with platelets of patients with Glanzmann thrombasthenia. This antibody doesn't appear to work for western blotting.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): No
Confirmed Species Reactivity: Human, Primate
Additional Information: 10E5 recognizes the alphaIIb in its native conformation associated to beta3 integrin.
Recommended Applications: ELISA, FACS, Function Blocking, Immunoprecipitation