7H2
Catalog Fields
Clone ID/Product Name: 7H2
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: ITGB3
Ab Isotype: MIgG1
Gene Name:
Antibody Registry ID: AB_2617394
Uniprot ID: P05106
Entrez Gene ID: 3690
Clonality: Monoclonal
Immunogen: Human platelets
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: X63-Ag8.653
Epitope Mapped: Yes
Antigen Name: integrin beta-3 (CD61), human
Epitope Location or Sequence: integrin beta3 PSI domain
Alternate Antigen Name:
Deposit Date: 5/2/2013
Antigen Molecular Weight: Predicted; 87 kDa; Apparent: 90 kDa
Depositor: Coller, B.S.
Antigen Sequence:
Depositor Institution: Rockefeller University
Antigen Species: Human
Depositor Notes: 7H2 reacts with alphaIIbbeta3 complex on platelets and has variable effects on platelet function. The epitope recognized by 7H2 is located on the beta3 PSI domain (unpublished mutational analysis).
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): No
Confirmed Species Reactivity: Human, Primate
Additional Information: 7H2 recognizes free beta3 as weel as alphaVbeta3 and alphaIIbbeta3 and their pro-forms. In immunoblots, 7H2 doesn't recognize its target under reducing conditions.
Recommended Applications: FACS, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot