Clone ID / Name: 7H2
Anti - integrin beta-3 (CD61), human
Catalog Fields
Identity
Clone ID / Name: 7H2
Alternate Antibody Name: —
Antigen Name: integrin beta-3 (CD61), human
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: ITGB3
Entrez Gene ID: 3690
Antigen Sequence: —
Antigen Species: Human
Antigen Mol. Weight: Predicted; 87 kDa; Apparent: 90 kDa
Uniprot ID: P05106
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: X63-Ag8.653
Antibody Registry / RRID: AB_2617394
Available to For-Profits: Yes
Hybridoma Available: No
Immunogen & Epitope
Immunogen: Human platelets
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: integrin beta3 PSI domain
Clone: —
Additional Info: 7H2 recognizes free beta3 as weel as alphaVbeta3 and alphaIIbbeta3 and their pro-forms. In immunoblots, 7H2 doesn't recognize its target under reducing conditions.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human, Primate
Predicted Reactivity: —
Depositor
Depositor Name: B.S. Coller
Institution: Rockefeller University
Deposit Date: May 2, 2013
Depositor Notes: 7H2 reacts with alphaIIbbeta3 complex on platelets and has variable effects on platelet function. The epitope recognized by 7H2 is located on the beta3 PSI domain (unpublished mutational analysis).
Recommended Applications
FACS
Function Blocking
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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