Product Name/ID: 8D9
Available to For-Profits: Yes
Alternate Antibody Name:
Ab Isotype: MIgG1
Immunogen: chick optic nerve
Myeloma Strain: NS1
Epitope Mapped: No
Antigen Name: L1-like CAM (avian)
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 2/20/1991
Antigen Molecular Weight: 190 kDa
Depositor: Lemmon, V.
Depositor Institution: Miami Project to Cure Paralysis, University of Miami Sch. of Med.
Antigen Species: chicken
Depositor Notes: Specificity note: Binds to surface of chick neurons, predominantly on their axons. Binds to chick but not to quail or mammals. Immunohistology note: stains tissue fixed with 2% paraformaldehyde and 0.01 glutaraldehyde, does not stain paraffin embedded tissue. IP note: antibody does not work on Western blots but is very useful for immunoprecipitations and affinity chromatography. Functional effects: polyclonal antibodies to 8D9 antigen inhibit axon fasciculation, 8D9 antigen is a potent substrate for neurite growth. IHC note: monoclonal antibody 8D9 gives intense staining of chick axons in vivo and in vitro.
Host Species: mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Chick
Predicted Species Reactivity:
Recommended Applications: Immunohistochemistry, Immunoprecipitation