Clone ID / Name: CBR LFA-1/2
Anti - Integrin beta-2 (CD18)
Catalog Fields
Identity
Clone ID / Name: CBR LFA-1/2
Alternate Antibody Name: —
Antigen Name: Integrin beta-2 (CD18)
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: ITGB2
Entrez Gene ID: 3689
Antigen Sequence: —
Antigen Species: Human
Antigen Mol. Weight: 84.7 kDa (core protein) 90-95 kDa (glycoprotein)
Uniprot ID: P05107
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: P3X63Ag8.653
Antibody Registry / RRID: AB_3094516
Available to For-Profits: No
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: LFA-1 purified by TS2/4 affinity chromatrography.
Immunogen Sequence: Full length sequence
Epitope Mapped: Yes
Epitope Location / Seq: Cytoplasmic domains involving residues 534, 536, 541, 543 and 546 in cysteine-rich repeat 3.
Clone: —
Additional Info: mAb CBR LFA-1/2 bindsing activates LFA-1 signaling.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human
Predicted Reactivity: —
Depositor
Depositor Name: T.A. Springer
Institution: Boston Children’s Hospital, Harvard University
Deposit Date: February 21, 2024
Depositor Notes: CD18 is associated with CD11a to form LFA-1 which binds to CD54, CD102 and CD50.
Recommended Applications
ChIP
ELISA
Function Blocking
IF
IHC
IP
Each lab must optimize concentration per application and species. Full usage recommendations →
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