CBR LFA-1/2

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Catalog Fields

Clone ID/Product Name: CBR LFA-1/2

Available to For-Profits: No

Alternate Antibody Name:

Gene Symbol: ITGB2

Ab Isotype: MIgG1

Gene Name:

Antibody Registry ID: AB_3094516

Uniprot ID: P05107

RRID:

Entrez Gene ID: 3689

Clonality: Monoclonal

Immunogen: LFA-1 purified by TS2/4 affinity chromatrography.

Clone:

Immunogen Sequence: Full length sequence

Myeloma Strain: P3X63Ag8.653

Epitope Mapped: Yes

Antigen Name: Integrin beta-2 (CD18)

Epitope Location or Sequence: Cytoplasmic domains involving residues 534, 536, 541, 543 and 546 in cysteine-rich repeat 3.

Alternate Antigen Name:

Deposit Date: 2/21/2024

Antigen Molecular Weight: 84.7 kDa (core protein) 90-95 kDa (glycoprotein)

Depositor: Springer, T.A.

Antigen Sequence:

Depositor Institution: Boston Children’s Hospital, Harvard University

Antigen Species: Human

Depositor Notes: CD18 is associated with CD11a to form LFA-1 which binds to CD54, CD102 and CD50.

Host Species: Mouse

Hybridoma Cells Available (Non-Profit): Yes

Confirmed Species Reactivity: Human

Additional Information: mAb CBR LFA-1/2 bindsing activates LFA-1 signaling.

Predicted Species Reactivity:

Human Protein Atlas:

Additional Characterization:

Recommended Applications: Chromatin Immunoprecipitation, ELISA, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation