K75/41

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$40.00
SKU: K75/41
View product citations for antibody K75/41 on CiteAb

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Available: 39

DSHB Data Sheet

Catalog Fields

Antigen: Kv4.3 K+ channel
Hybridoma Cells Available: Yes
Antigen Species: Rat
Depositor: Trimmer, J.S.
Isotype: MIgG1
Antigen Sequence:
Host Species: mouse
Depositors Institution: UC - Davis
Positive Tested Species Reactivity: Human, Mouse, Rat, Xenopus
Depositors Notes: This antibody does not cross-react with Kv4.2.
Antigen Molecular Weight: 70 kDa
Human Protein Atlas:  
Predicted Species Reactivity:  
Gene: KCND3
Immunogen: Recombinant fusion protein
Alternate Gene Names: KV4.3, BRGDA9
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: No
Myeloma Strain: SP2/0
Epitope Location or Sequence:
Uniprot ID: Q62897 
Immunogen Sequence: a.a. 415-636 (C-terminus)
Entrez Gene ID: 3752 
Additional Characterization:  
Antibody Registry ID:  
Additional Information: K75/41 specificity has been validated in KCND3 KO mice. PMID: 18045613
Recommended Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
K75/41 was deposited to the DSHB by Trimmer, J.S. (DSHB Hybridoma Product K75/41)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
Although the optimal Ig concentration for an application varies for each product and must be optimized for each laboratory, a good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) is 2-5 ug/ml. For western blots, the recommended concentration range is 0.2-0.5 ug/ml.
All cell products contain the antimicrobial ProClin. Click here for additional information.

9 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • ELISA References
  • All References
  • Initial Publication

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    IF References

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
    Rainnie DG
    Neuroscience 171.3 (2010 Dec 15): 721-33.

    The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.
    Trimmer JS
    Epilepsia 53 Suppl 1. (2012 Jun): 142-9.

    Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.
    Nerbonne JM
    The Journal of neuroscience : the official journal of the Society for Neuroscience 26.47 (2006 Nov 22): 12274-82.

    WB References

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    KChIP2 is a core transcriptional regulator of cardiac excitability.
    Deschênes I
    eLife 6. (2017 Mar 6): .

    Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.
    Xu H
    International journal of molecular medicine 36.1 (2015 Jul): 309-15.

    IHC References

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 26.47 (2006 Nov 22): 12137-42.

    Functional specification of CCK+ interneurons by alternative isoforms of Kv4.3 auxiliary subunits.
    Szabadics J
    eLife 9. (2020 Jun 3): .

    K<sup>+</sup> Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.
    Tsaur ML
    The Journal of neuroscience : the official journal of the Society for Neuroscience 37.16 (2017 Apr 19): 4391-4404.

    ELISA References

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    All References

    KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 24.36 (2004 Sep 8): 7903-15.

    Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain.
    Trimmer JS
    The Journal of neuroscience : the official journal of the Society for Neuroscience 26.47 (2006 Nov 22): 12137-42.

    Functional specification of CCK+ interneurons by alternative isoforms of Kv4.3 auxiliary subunits.
    Szabadics J
    eLife 9. (2020 Jun 3): .

    K<sup>+</sup> Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.
    Tsaur ML
    The Journal of neuroscience : the official journal of the Society for Neuroscience 37.16 (2017 Apr 19): 4391-4404.

    Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
    Rainnie DG
    Neuroscience 171.3 (2010 Dec 15): 721-33.

    The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.
    Trimmer JS
    Epilepsia 53 Suppl 1. (2012 Jun): 142-9.

    Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.
    Nerbonne JM
    The Journal of neuroscience : the official journal of the Society for Neuroscience 26.47 (2006 Nov 22): 12274-82.

    KChIP2 is a core transcriptional regulator of cardiac excitability.
    Deschênes I
    eLife 6. (2017 Mar 6): .

    Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.
    Xu H
    International journal of molecular medicine 36.1 (2015 Jul): 309-15.

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