K87A/10
Catalog Fields
Clone ID/Product Name: K87A/10
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: Scn8a
Ab Isotype: MIgG1
Gene Name:
Antibody Registry ID: AB_2877193
Uniprot ID: O88420
Entrez Gene ID: 29710
Clonality: Monoclonal
Immunogen: GST-fusion protein
Clone:
Immunogen Sequence: a.a. 459-476 (intracellular interdomain loop I-II)
Myeloma Strain: SP2/0
Epitope Mapped: Yes
Antigen Name: Sodium channel protein type 8 subunit alpha (Nav1.6 Na+ channel)
Epitope Location or Sequence: a.a. 459-476
Alternate Antigen Name:
Deposit Date: 2/21/2019
Antigen Molecular Weight: 225.2 kDa (predicted)
Depositor: Trimmer, J.S.
Antigen Sequence:
Depositor Institution: UC - Davis
Antigen Species: Rat
Depositor Notes: K87A/10 does not work well in western blot applications.
Host Species: mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Human, Mouse, Rat
Additional Information: K87A/10 specificity has been validated in Nav1.6 null mice. PMID: 19261867.
Recommended Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation
All cell products contain the antimicrobial ProClin. Click here for additional information.
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
K87A/10 was deposited to the DSHB by Trimmer, J.S. (DSHB Hybridoma Product K87A/10)
Storage and Handling Recommendations
Usage Recommendations
6 References
Initial Publication
Functional specialization of the axon initial segment by isoform-specific sodium channel targeting.
Matthews G
The Journal of neuroscience : the official journal of the Society for Neuroscience 23.6 (2003 Mar 15): 2306-13.