K87A/10
Catalog Fields
Antigen: Sodium channel protein type 8 subunit alpha (Nav1.6 Na+ channel)
Available to For-Profits: Yes
Antigen Species: Rat
Hybridoma Cells Available (Non-Profit): Yes
Isotype: MIgG1
Depositor: Trimmer, J.S.
Host Species: mouse
Antigen Sequence:
Positive Tested Species Reactivity: Human, Mouse, Rat
Depositors Institution: UC - Davis
Antigen Molecular Weight: 225.2 kDa (predicted)
Depositors Notes: K87A/10 does not work well in western blot applications.
Immunogen: GST-fusion protein
Gene: Scn8a
Alternate Antibody Name:
Alternate Gene Names: Nbna1
Alternate Antigen Name:
Clonality: Monoclonal
Myeloma Strain: SP2/0
Epitope Mapped: Yes
Uniprot ID: O88420
Epitope Location or Sequence: a.a. 459-476
Entrez Gene ID: 29710
Immunogen Sequence: a.a. 459-476 (intracellular interdomain loop I-II)
Recommended Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Additional Information: K87A/10 specificity has been validated in Nav1.6 null mice. PMID: 19261867.
All cell products contain the antimicrobial ProClin. Click here for additional information.
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
K87A/10 was deposited to the DSHB by Trimmer, J.S. (DSHB Hybridoma Product K87A/10)
Storage and Handling Recommendations
Usage Recommendations
6 References
Initial Publication
Functional specialization of the axon initial segment by isoform-specific sodium channel targeting.
Matthews G
The Journal of neuroscience : the official journal of the Society for Neuroscience 23.6 (2003 Mar 15): 2306-13.