Antibody Name: LM2/1.6.11
Antigen:CD11b (Integrin alpha-M, Mac-1 alpha chain), human
Catalog Fields
Identity
Clone ID / Antibody Name: LM2/1.6.11
Alternate Antibody Name: LM2/1
Antigen Name: CD11b (Integrin alpha-M, Mac-1 alpha chain), human
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: ITGAM
Entrez Gene ID: 3684
Antigen Sequence: —
Antigen Species: Human
Antigen Mol. Weight: Predicted: 127 kDa; Apparent: 170 kDa
Uniprot ID: P11215
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: P3X63Ag8.6.5.3
Antibody Registry / RRID: AB_528135
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: CD11b immunoprecipitated from Human granulocyte lysates + boost with Human live granulocytes.
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: I domain (aa 148-332)
Clone: —
Additional Info: Mac-1 is a macrophage differentiation antigen and a marker for microglia.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human
Predicted Reactivity: —
Depositor
Depositor Name: T.A. Springer
Institution: Center for Blood Research, Boston
Deposit Date: April 4, 1989
Depositor Notes: Does not cross react with mouse. Does not block iC3B rosetting. Binds to granulocytes, monocytes, macrophages, CD5+ B cells, hairy cell leukemia cells. Doesn't work well for western blotting.
Recommended Applications
FACS
Function Blocking
IF
IHC
IP
Each lab must optimize concentration per application and species. Full usage recommendations →
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