Antibody Name: P1F6
Antigen:integrin alpha V beta 5 (CD51, fibronectin/vitronectin receptor)
Catalog Fields
Identity
Clone ID / Antibody Name: P1F6
Alternate Antibody Name: CD49e, CD51
Antigen Name: integrin alpha V beta 5 (CD51, fibronectin/vitronectin receptor)
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: ITGAV/ITGB5
Antigen Sequence: —
Antigen Species: Human
Antigen Mol. Weight: Apparent: 160 kDa (alpha chain), 95 kDa (beta chain)
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: NS-1/FOX-NY
Antibody Registry / RRID: AB_2619586
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: small cell lung carcinoma from the UCLA P3 cell line expressing the vitronectin receptor.
Immunogen Sequence: Full length protein
Epitope Mapped: No
Epitope Location / Seq: —
Clone: —
Additional Info: P1F6 recognizes a composite epitope on alphaV/beta5 native heterodimer integrin.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Chicken, Hamster, Human, Rat
Predicted Reactivity: —
Depositor
Depositor Name: E.A. Wayner
Institution: Fred Hutchinson Cancer Research Center
Deposit Date: October 11, 2011
Depositor Notes: Immunostaining works only on acetone fixed preps. P1F6 completely inhibits alphaVbeta5 dependent binding to vitronectin-coated substrates. Doesn't cross-reactwith alphaVbeta3.
Recommended Applications
ELISA
FACS
Function Blocking
IF
IHC
IP
Each lab must optimize concentration per application and species. Full usage recommendations →