Ror2

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$40.00
SKU: Ror2
View product citations for antibody Ror2 on CiteAb

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DSHB Data Sheet

Catalog Fields

Antigen: Receptor tyrosine kinase-like orphan receptor 2/Ror2
Hybridoma Cells Available: Yes
Antigen Species: Mouse
Depositor: Nusse, R.
Isotype: MIgG1
Antigen Sequence:
Host Species: mouse
Depositors Institution: Stanford University
Positive Tested Species Reactivity: Human, Mouse
Depositors Notes: This antibody does not cross react with Ror1. The antigen is also known as neurotrophic tyrosine kinase, receptor-related 2 and is involved in cartilage growth, growth plate development and hair follicle patterning.
Antigen Molecular Weight: 105 kDa
Human Protein Atlas:  
Predicted Species Reactivity:  
Gene: Ror2
Immunogen: Ror2-MBP fusion protein
Alternate Gene Names: Ntrkr2, mRor2
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: Yes
Myeloma Strain:
Epitope Location or Sequence: C-terminus
Uniprot ID: Q9Z138 
Immunogen Sequence: NT 2535-2835/ C-terminal 100 amino acids
Entrez Gene ID: 26564 
Additional Characterization:  
Antibody Registry ID: AB_10804796 
Additional Information:
Recommended Applications: ELISA, FFPE, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
Ror2 was deposited to the DSHB by Nusse, R. (DSHB Hybridoma Product Ror2)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
Although the optimal Ig concentration for an application varies for each product and must be optimized for each laboratory, a good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) is 2-5 ug/ml. For western blots, the recommended concentration range is 0.2-0.5 ug/ml.
All cell products contain the antimicrobial ProClin. Click here for additional information.

5 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • IP References
  • ELISA References
  • FFPE References
  • Epitope Map References
  • All References
  • Initial Publication

    Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
    Nusse R
    The Journal of biological chemistry 284.44 (2009 Oct 30): 30167-76.

    IF References

    Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
    Nusse R
    The Journal of biological chemistry 284.44 (2009 Oct 30): 30167-76.

    Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.
    Rosen JM
    The Journal of cell biology 208.3 (2015 Feb 2): 351-66.

    Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2.
    Yang Y
    Developmental cell 20.2 (2011 Feb 15): 163-76.

    WB References
    IHC References
    IP References
    ELISA References

    Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
    Nusse R
    The Journal of biological chemistry 284.44 (2009 Oct 30): 30167-76.

    FFPE References

    Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
    Nusse R
    The Journal of biological chemistry 284.44 (2009 Oct 30): 30167-76.

    Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.
    Rosen JM
    The Journal of cell biology 208.3 (2015 Feb 2): 351-66.

    Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.
    Nusse R
    Developmental biology 369.1 (2012 Sep 1): 101-14.

    Epitope Map References

    Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
    Nusse R
    The Journal of biological chemistry 284.44 (2009 Oct 30): 30167-76.

    All References

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