Antibody Name: sm 1.2
Antigen:somatomedin-C; Sm-C/IGF-1
Catalog Fields
Identity
Clone ID / Antibody Name: sm 1.2
Alternate Antibody Name: —
Antigen Name: somatomedin-C; Sm-C/IGF-1
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: —
Entrez Gene ID: —
Antigen Sequence: —
Antigen Species: human
Antigen Mol. Weight: 7.5 kDa
Uniprot ID: —
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: P3X63Ag8.653
Antibody Registry / RRID: AB_2233416
Available to For-Profits: Yes
Hybridoma Available: No
Immunogen & Epitope
Immunogen: —
Immunogen Sequence: —
Epitope Mapped: No
Epitope Location / Seq: —
Clone: —
Additional Info: —
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Chick, Human, Mouse, Rat
Predicted Reactivity: —
Depositor
Depositor Name: J.J. Van Wyk / L.E. Underwood
Institution: University of North Carolina Chapel Hill
Deposit Date: June 3, 1987
Depositor Notes: Species specificity note: cross-reacts with human, rat, mouse, and possibly chick; occasional difficulty neutralizing rat somatomedin due to binding protein interference. Cell binding note: demonstrated in Sertoli cells, testicular peritubular cells, brain cells, liver cells and many other cell types. Antibody competition: cross-reacts with IGF-II but not other peptide hormones. Blotting note: single band in Western blot with polyclonal Ab. Purification note: single band on PAGE with silver stain. Functional effects: promotes cell replication and differentiation in wide variety of in vitro systems. IHC note: in situ hybridization histochemistry reveals origin in mesenchymally derived tissues (Han et al., Science (1987). 236, 193-196.), but immunofluorescence shows more diffuse localization (Han et al., Pediatr. Res. (1987).
Recommended Applications
IF
IHC
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
UniProt DataUniProtNo UniProt ID
▼No UniProt ID is available for this product.