2B49
Catalog Fields
Clone ID/Product Name: 2B49
Available to For-Profits: Yes
Alternate Antibody Name: protein tyrosine phosphatase - z/b
Gene Symbol: Ptprz1
Ab Isotype: MIgG1
Gene Name:
Antibody Registry ID: AB_2173126
Uniprot ID: Q62656
Entrez Gene ID: 25613
Clonality: Monoclonal
Immunogen: PBS-soluble chondroitin sulfate proteoglycans from rat brain
Clone:
Immunogen Sequence:
Myeloma Strain: PAI
Epitope Mapped: No
Antigen Name: phosphacan/protein tyrosine phosphatase - z/b
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 1/27/1998
Antigen Molecular Weight:
Depositor: Margolis, R.K. / Margolis, R.U.
Antigen Sequence:
Depositor Institution: New York University Medical Center / State University of New York
Antigen Species: rat
Depositor Notes: For immunocytochemistry use ascites at dilutions of 1:100-1:500. However, frequently grows as solid tumors, so yield of ascites may be very small. Hybridoma supernatant is most economical for use with immunoblots.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Rat
Additional Information: Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades RRID:AB_2173126
Recommended Applications: Immunohistochemistry, Western Blot