Antibody Name: 2B49

Antigen:phosphacan/protein tyrosine phosphatase - z/b
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$50.00
SKU: 2B49
~ 13 – 18 μg/mL
N/A
N/A
iConcentration varies between lots. Lots are distributed in the order they are produced.

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Catalog Fields
Identity
Clone ID / Antibody Name: 2B49
Alternate Antibody Name: protein tyrosine phosphatase - z/b
Antigen Name: phosphacan/protein tyrosine phosphatase - z/b
Alternate Antigen Name: 
Gene Symbol: 
Gene Name: Ptprz1
Entrez Gene ID: 25613
Antigen Sequence: 
Antigen Species: rat
Antigen Mol. Weight: 
Uniprot ID: Q62656
Human Protein Atlas: 
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: PAI
Antibody Registry / RRID: AB_2173126
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: PBS-soluble chondroitin sulfate proteoglycans from rat brain
Immunogen Sequence: 
Epitope Mapped: No
Epitope Location / Seq: 
Clone: 
Additional Info: Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades RRID:AB_2173126
Add. Characterization: 
Species Reactivity
Confirmed Reactivity: Rat
Predicted Reactivity: 
Depositor
Depositor Name: R.K. Margolis / R.U. Margolis
Institution: New York University Medical Center / State University of New York
Deposit Date: January 27, 1998
Depositor Notes: For immunocytochemistry use ascites at dilutions of 1:100-1:500. However, frequently grows as solid tumors, so yield of ascites may be very small. Hybridoma supernatant is most economical for use with immunoblots.
Recommended Applications
IHC
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
UniProt DataUniProtQ62656 ↗
Could not load UniProt data for Q62656

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