Antibody Name: P1E6
Antigen:integrin alpha 2 (CD49b)
Catalog Fields
Identity
Clone ID / Antibody Name: P1E6
Alternate Antibody Name: CD49b
Antigen Name: integrin alpha 2 (CD49b)
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: ITGA2
Entrez Gene ID: 3673
Antigen Sequence: —
Antigen Species: Human
Antigen Mol. Weight: Predicted: 129 kDa; Apparent: 150 kDa
Uniprot ID: P17301
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: NS-1/FOX-NY
Antibody Registry / RRID: AB_2619597
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Human HT-1080 fibrosarcoma cells
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: I domain (aa 169-378 of Uniprot ID P17301-1)
Clone: —
Additional Info: P1E6 recognizes an epitope that requires activation of the alpha2/beta1 complex.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human
Predicted Reactivity: —
Depositor
Depositor Name: E.A. Wayner / W.G. Carter
Institution: Fred Hutchinson Cancer Research Center
Deposit Date: October 11, 2011
Depositor Notes: Inhibits binding to collagens I, III, IV and VI. Will IP alpha2 beta1 complex (non-reducing). Immunoblotting works under non-reducing conditions. Immunostaining with frozen or acetone fixation (not formalin). Doesn't work for FFPE.
Recommended Applications
FACS
Function Blocking
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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