AIIB2

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$40.00
SKU: AIIB2
View product citations for antibody AIIB2 on CiteAb

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Available: 300

DSHB Data Sheet

Catalog Fields

Antigen: Integrin, beta-1 subunit
Hybridoma Cells Available: Yes
Antigen Species: Human
Depositor: Damsky, C.H.
Isotype: RIgG1, kappa light chain
Antigen Sequence:
Host Species: rat
Depositors Institution: University of California, San Francisco
Positive Tested Species Reactivity: Bovine, Canine, Human, Mouse, Sheep
Depositors Notes: Blocks cell attachment to fibronectin, collagen-I, collagen-IV, laminin. This antibody stains aldehyde fixed cells and frozen sections of fixed tissues. Does not appear to work for immunoblotting. Binds protein G.
Antigen Molecular Weight: Predicted: 88kDa (multiple isoforms 87 to 92kDa); Apparent: 110kDa non-reduced gel mobility, 130kDa reduced gel mobility
Human Protein Atlas:
Predicted Species Reactivity:  
Gene: ITGB1
Immunogen: Whole JAR choriocarcinoma trophoblastic cell line
Alternate Gene Names: CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: Yes
Myeloma Strain: SP 2/0
Epitope Location or Sequence: NKGEVFNELVGK (a.a. 207-218)
Uniprot ID: P05556 
Immunogen Sequence: Full length protein
Entrez Gene ID: 3688 
Additional Characterization:
Antibody Registry ID: AB_528306 
Additional Information: Like most anti-integrin antibodies, AIIB2 does not blot well. Refer to the cited papers for protocols required for western blotting.
Recommended Applications: ELISA, FACS, FFPE, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
AIIB2 was deposited to the DSHB by Damsky, C.H. (DSHB Hybridoma Product AIIB2)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. To ensure retention of antibody activity, we recommend aliquotting the product into two parts: 1) a volume of antibody stored at 4°C to be used within two weeks. 2) the remaining product diluted with an equal volume of molecular grade glycerol and stored at -20°C.
Usage Recommendations
While optimal Ig concentration for an application will vary, a good starting concentration for immunohistochemistry (IHC), immunofluorescence(IF) and staining is 2-5 µg/ml. For Western blots, the concentration is decreased by one order of magnitude (that is, 0.2-0.5 µg/ml).
All cell products contain the antimicrobial ProClin. Click here for additional information.

77 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • IP References
  • ELISA References
  • FFPE References
  • FB References
  • FACS References
  • Epitope Map References
  • All References
  • Initial Publication
    IF References

    Adhesion receptors mediate efficient non-viral gene delivery.
    Hoekstra D
    Molecular therapy : the journal of the American Society of Gene Therapy 15.5 (2007 May): 946-53.

    Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.
    Hauck SM
    PloS one 8.7 (2013): e70011.

    Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
    Gonias SL
    Cancer research 70.21 (2010 Nov 1): 8948-58.

    Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel.
    Haga H
    PloS one 9.8 (2014): e99655.

    The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis.
    Grinstein S
    Molecular biology of the cell 25.9 (2014 May): 1511-22.

    Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.
    Müsch A
    The Journal of cell biology 203.2 (2013 Oct 28): 251-64.

    The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.
    Sumimoto H
    The Journal of cell biology 200.5 (2013 Mar 4): 635-50.

    Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways.
    Coppolino MG
    BMC cell biology 11. (2010 Aug 10): 62.

    Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration.
    Philp NJ
    American journal of physiology. Cell physiology 296.3 (2009 Mar): C414-21.

    Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells.
    Cordes N
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 92.3 (2009 Sep): 362-70.

    beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms.
    Watt FM
    Molecular biology of the cell 11.2 (2000 Feb): 453-66.

    Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1.
    Vande Pol SB
    Virology 355.1 (2006 Nov 10): 102-14.

    Integrin beta1-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.
    Nishioka T
    Biochemical and biophysical research communications 396.3 (2010 Jun 4): 651-5.

    Modulation of radiation-induced oral mucositis (mouse) by selective inhibition of β1 integrin.
    Dörr W
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 104.2 (2012 Aug): 230-4.

    Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts.
    Fisher SJ
    The Journal of clinical investigation 91.3 (1993 Mar): 950-60.

    Integrin switching regulates normal trophoblast invasion.
    Fisher SJ
    Development (Cambridge, England) 120.12 (1994 Dec): 3657-66.

    PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer.
    Novaro V
    Carcinogenesis 33.3 (2012 Mar): 509-18.

    Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions.
    Chen J
    The Journal of biological chemistry 291.19 (2016 May 6): 10363-71.

    WB References

    Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells.
    Cordes N
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 92.3 (2009 Sep): 362-70.

    Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit.
    Smolka AJ
    Gastroenterology 139.1 (2010 Jul): 239-48.

    SHARPIN is an endogenous inhibitor of β1-integrin activation.
    Ivaska J
    Nature cell biology 13.11 (2011 Sep 25): 1315-24.

    IHC References
    IP References

    Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
    Damsky CH
    The Journal of cell biology 109.2 (1989 Aug): 877-89.

    Adhesion receptors mediate efficient non-viral gene delivery.
    Hoekstra D
    Molecular therapy : the journal of the American Society of Gene Therapy 15.5 (2007 May): 946-53.

    Synthesis and expression of the fibroblast fibronectin receptor in human monocytes.
    Charo IF
    The Journal of clinical investigation 84.1 (1989 Jul): 366-70.

    Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.
    Puzon W
    The Journal of biological chemistry 268.23 (1993 Aug 15): 17597-601.

    Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways.
    Zegers MM
    PloS one 7.7 (2012): e41039.

    Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit.
    Smolka AJ
    Gastroenterology 139.1 (2010 Jul): 239-48.

    Calcium-sensing receptor modulates cell adhesion and migration via integrins.
    Hampson DR
    The Journal of biological chemistry 286.47 (2011 Nov 25): 40922-33.

    Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration.
    Philp NJ
    American journal of physiology. Cell physiology 296.3 (2009 Mar): C414-21.

    Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells.
    Cordes N
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 92.3 (2009 Sep): 362-70.

    Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1.
    Vande Pol SB
    Virology 355.1 (2006 Nov 10): 102-14.

    ELISA References

    Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.
    Ivaska J
    The Journal of cell biology 173.5 (2006 Jun 5): 767-80.

    FFPE References
    FB References

    Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
    Damsky CH
    The Journal of cell biology 109.2 (1989 Aug): 877-89.

    ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
    Wewer UM
    FEBS letters 579.25 (2005 Oct 24): 5589-95.

    Hierarchy of ADAM12 binding to integrins in tumor cells.
    Wewer UM
    Experimental cell research 309.2 (2005 Oct 1): 438-50.

    Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling.
    Ossowski L
    The Journal of cell biology 147.1 (1999 Oct 4): 89-104.

    beta1-integrin cytoplasmic subdomains involved in dominant negative function.
    Tarone G
    Molecular biology of the cell 9.4 (1998 Apr): 715-31.

    Adhesion receptors mediate efficient non-viral gene delivery.
    Hoekstra D
    Molecular therapy : the journal of the American Society of Gene Therapy 15.5 (2007 May): 946-53.

    Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER.
    Koch M
    The Biochemical journal 459.1 (2014 Apr 1): 217-27.

    Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model.
    Cress AE
    Molecular cancer therapeutics 13.6 (2014 Jun): 1558-66.

    Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex.
    Barker TH
    Nature communications 5. (2014 Sep 12): 4886.

    MicroRNA 9-3p targets β1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition.
    Johnson GL
    Molecular and cellular biology 33.11 (2013 Jun): 2260-74.

    β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy.
    Cordes N
    The Journal of clinical investigation 122.4 (2012 Apr): 1529-40.

    Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells.
    Hartley RS
    Breast cancer research and treatment 127.2 (2011 Jun): 397-406.

    β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells.
    Defilippi P
    Oncogene 30.39 (2011 Sep 29): 4087-96.

    β1 integrin regulates MMP-10 dependant tubulogenesis in human lymphatic endothelial cells.
    Tempero RM
    Matrix biology : journal of the International Society for Matrix Biology 30.3 (2011 Apr): 218-24.

    Allosteric modulation of beta1 integrin function induces lung tissue repair.
    Harrison DJ
    Advances in pharmacological sciences 2012. (2012): 768720.

    Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells.
    Ferrero RL
    Infection and immunity 78.11 (2010 Nov): 4523-31.

    Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.
    Schmaier AH
    Blood 115.24 (2010 Jun 17): 5111-20.

    Polydom/SVEP1 is a ligand for integrin α9β1.
    Sekiguchi K
    The Journal of biological chemistry 287.30 (2012 Jul 20): 25615-30.

    Receptor expression changes as a basis for endothelial cell identification using microfluidic channels.
    Murthy SK
    Lab on a chip 10.18 (2010 Sep 21): 2380-6.

    The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins.
    Williams JV
    Journal of virology 86.22 (2012 Nov): 12148-60.

    Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo.
    Bissell MJ
    Cancer research 66.3 (2006 Feb 1): 1526-35.

    Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel.
    Haga H
    PloS one 9.8 (2014): e99655.

    Chondrocyte culture in three dimensional alginate sulfate hydrogels promotes proliferation while maintaining expression of chondrogenic markers.
    Zenobi-Wong M
    Tissue engineering. Part A 20.9-10 (2014 May): 1454-64.

    Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions.
    Haga H
    Experimental cell research 319.19 (2013 Nov 15): 2916-27.

    Beta 1 integrin binding plays a role in the constant traction force generation in response to varying stiffness for cells grown on mature cardiac extracellular matrix.
    Black LD 3rd
    Experimental cell research 330.2 (2015 Jan 15): 311-24.

    Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2.
    Schmaier AH
    American journal of physiology. Heart and circulatory physiology 305.3 (2013 Aug 1): H305-20.

    A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system.
    Kwok T
    Cellular microbiology 15.4 (2013 Apr): 554-70.

    Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells.
    Wedlich-Soldner R
    The Journal of cell biology 207.1 (2014 Oct 13): 107-21.

    Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.
    Müsch A
    The Journal of cell biology 203.2 (2013 Oct 28): 251-64.

    Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways.
    Zegers MM
    PloS one 7.7 (2012): e41039.

    A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II.
    Wewer UM
    Molecular and cellular biology 32.10 (2012 May): 1788-804.

    Inhibition of tissue factor signaling suppresses tumor growth.
    Ruf W
    Blood 111.1 (2008 Jan 1): 190-9.

    Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment.
    Gupta N
    Journal of neuro-oncology 86.2 (2008 Jan): 133-41.

    Shear stress activation of SREBP1 in endothelial cells is mediated by integrins.
    Shyy JY
    Arteriosclerosis, thrombosis, and vascular biology 22.1 (2002 Jan): 76-81.

    Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration.
    Shimizu Y
    Journal of immunology (Baltimore, Md. : 1950) 164.3 (2000 Feb 1): 1143-7.

    Cross-talk of integrin alpha3beta1 and tissue factor in cell migration.
    Ruf W
    Molecular biology of the cell 15.10 (2004 Oct): 4416-25.

    Alpha(v)beta3 and alpha(v)beta5 integrins bind both the proximal RGD site and non-RGD motifs within noncollagenous (NC1) domain of the alpha3 chain of type IV collagen: implication for the mechanism of endothelia cell adhesion.
    Hudson BG
    The Journal of biological chemistry 279.4 (2004 Jan 23): 2772-80.

    Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.
    Cress AE
    Carcinogenesis 27.9 (2006 Sep): 1748-57.

    Integrin beta1-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.
    Nishioka T
    Biochemical and biophysical research communications 396.3 (2010 Jun 4): 651-5.

    Modulation of radiation-induced oral mucositis (mouse) by selective inhibition of β1 integrin.
    Dörr W
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 104.2 (2012 Aug): 230-4.

    Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.
    Kermorgant S
    Nature communications 7. (2016 Jun 23): 11942.

    A mechanism for asymmetric cell division resulting in proliferative asynchronicity.
    Ramaswamy S
    Molecular cancer research : MCR 13.2 (2015 Feb): 223-30.

    The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin.
    Taskén K
    The Journal of biological chemistry 279.43 (2004 Oct 22): 44889-96.

    Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells.
    Cress AE
    Journal of cellular biochemistry 118.5 (2017 May): 1038-1049.

    Recombinant laminin-8 (alpha(4)beta(1)gamma(1)). Production, purification,and interactions with integrins.
    Tryggvason K
    The Journal of biological chemistry 275.20 (2000 May 19): 14853-9.

    Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.
    Timpl R
    The Journal of cell biology 110.6 (1990 Jun): 2145-55.

    The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.
    Damsky CH
    The Journal of cell biology 110.6 (1990 Jun): 2175-84.

    Live cell measurements of interaction forces and binding kinetics between Discoidin Domain Receptor 1 (DDR1) and collagen I with atomic force microscopy.
    Hoffmann PM
    Biochimica et biophysica acta. General subjects 1863.11 (2019 Nov): 129402.

    FACS References

    ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
    Wewer UM
    FEBS letters 579.25 (2005 Oct 24): 5589-95.

    Hierarchy of ADAM12 binding to integrins in tumor cells.
    Wewer UM
    Experimental cell research 309.2 (2005 Oct 1): 438-50.

    Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling.
    Ossowski L
    The Journal of cell biology 147.1 (1999 Oct 4): 89-104.

    The androgen receptor induces integrin α6β1 to promote prostate tumor cell survival via NF-κB and Bcl-xL Independently of PI3K signaling.
    Miranti CK
    Cancer research 71.7 (2011 Apr 1): 2739-49.

    Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling.
    Mercurio AM
    Journal of cell science 125.Pt 2 (2012 Jan 15): 497-506.

    The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins.
    Williams JV
    Journal of virology 86.22 (2012 Nov): 12148-60.

    Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo.
    Bissell MJ
    Cancer research 66.3 (2006 Feb 1): 1526-35.

    Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.
    Puzon W
    The Journal of biological chemistry 268.23 (1993 Aug 15): 17597-601.

    Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions.
    Chen J
    The Journal of biological chemistry 291.19 (2016 May 6): 10363-71.

    Epitope Map References

    Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.
    Puzon W
    The Journal of biological chemistry 268.23 (1993 Aug 15): 17597-601.

    All References

    PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer.
    Novaro V
    Carcinogenesis 33.3 (2012 Mar): 509-18.

    Adhesion receptors mediate efficient non-viral gene delivery.
    Hoekstra D
    Molecular therapy : the journal of the American Society of Gene Therapy 15.5 (2007 May): 946-53.

    Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.
    Hauck SM
    PloS one 8.7 (2013): e70011.

    Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
    Gonias SL
    Cancer research 70.21 (2010 Nov 1): 8948-58.

    Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel.
    Haga H
    PloS one 9.8 (2014): e99655.

    The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis.
    Grinstein S
    Molecular biology of the cell 25.9 (2014 May): 1511-22.

    Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.
    Müsch A
    The Journal of cell biology 203.2 (2013 Oct 28): 251-64.

    The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.
    Sumimoto H
    The Journal of cell biology 200.5 (2013 Mar 4): 635-50.

    Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways.
    Coppolino MG
    BMC cell biology 11. (2010 Aug 10): 62.

    Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration.
    Philp NJ
    American journal of physiology. Cell physiology 296.3 (2009 Mar): C414-21.

    Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells.
    Cordes N
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 92.3 (2009 Sep): 362-70.

    beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms.
    Watt FM
    Molecular biology of the cell 11.2 (2000 Feb): 453-66.

    Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1.
    Vande Pol SB
    Virology 355.1 (2006 Nov 10): 102-14.

    Integrin beta1-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.
    Nishioka T
    Biochemical and biophysical research communications 396.3 (2010 Jun 4): 651-5.

    Modulation of radiation-induced oral mucositis (mouse) by selective inhibition of β1 integrin.
    Dörr W
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 104.2 (2012 Aug): 230-4.

    Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts.
    Fisher SJ
    The Journal of clinical investigation 91.3 (1993 Mar): 950-60.

    Integrin switching regulates normal trophoblast invasion.
    Fisher SJ
    Development (Cambridge, England) 120.12 (1994 Dec): 3657-66.

    Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions.
    Chen J
    The Journal of biological chemistry 291.19 (2016 May 6): 10363-71.

    Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit.
    Smolka AJ
    Gastroenterology 139.1 (2010 Jul): 239-48.

    SHARPIN is an endogenous inhibitor of β1-integrin activation.
    Ivaska J
    Nature cell biology 13.11 (2011 Sep 25): 1315-24.

    Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.
    Damsky CH
    The Journal of cell biology 109.2 (1989 Aug): 877-89.

    Synthesis and expression of the fibroblast fibronectin receptor in human monocytes.
    Charo IF
    The Journal of clinical investigation 84.1 (1989 Jul): 366-70.

    Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.
    Puzon W
    The Journal of biological chemistry 268.23 (1993 Aug 15): 17597-601.

    Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways.
    Zegers MM
    PloS one 7.7 (2012): e41039.

    Calcium-sensing receptor modulates cell adhesion and migration via integrins.
    Hampson DR
    The Journal of biological chemistry 286.47 (2011 Nov 25): 40922-33.

    Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.
    Ivaska J
    The Journal of cell biology 173.5 (2006 Jun 5): 767-80.

    ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
    Wewer UM
    FEBS letters 579.25 (2005 Oct 24): 5589-95.

    Hierarchy of ADAM12 binding to integrins in tumor cells.
    Wewer UM
    Experimental cell research 309.2 (2005 Oct 1): 438-50.

    Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling.
    Ossowski L
    The Journal of cell biology 147.1 (1999 Oct 4): 89-104.

    beta1-integrin cytoplasmic subdomains involved in dominant negative function.
    Tarone G
    Molecular biology of the cell 9.4 (1998 Apr): 715-31.

    Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER.
    Koch M
    The Biochemical journal 459.1 (2014 Apr 1): 217-27.

    Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model.
    Cress AE
    Molecular cancer therapeutics 13.6 (2014 Jun): 1558-66.

    Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex.
    Barker TH
    Nature communications 5. (2014 Sep 12): 4886.

    MicroRNA 9-3p targets β1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition.
    Johnson GL
    Molecular and cellular biology 33.11 (2013 Jun): 2260-74.

    β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy.
    Cordes N
    The Journal of clinical investigation 122.4 (2012 Apr): 1529-40.

    Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells.
    Hartley RS
    Breast cancer research and treatment 127.2 (2011 Jun): 397-406.

    β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells.
    Defilippi P
    Oncogene 30.39 (2011 Sep 29): 4087-96.

    β1 integrin regulates MMP-10 dependant tubulogenesis in human lymphatic endothelial cells.
    Tempero RM
    Matrix biology : journal of the International Society for Matrix Biology 30.3 (2011 Apr): 218-24.

    Allosteric modulation of beta1 integrin function induces lung tissue repair.
    Harrison DJ
    Advances in pharmacological sciences 2012. (2012): 768720.

    Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells.
    Ferrero RL
    Infection and immunity 78.11 (2010 Nov): 4523-31.

    Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.
    Schmaier AH
    Blood 115.24 (2010 Jun 17): 5111-20.

    Polydom/SVEP1 is a ligand for integrin α9β1.
    Sekiguchi K
    The Journal of biological chemistry 287.30 (2012 Jul 20): 25615-30.

    Receptor expression changes as a basis for endothelial cell identification using microfluidic channels.
    Murthy SK
    Lab on a chip 10.18 (2010 Sep 21): 2380-6.

    The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins.
    Williams JV
    Journal of virology 86.22 (2012 Nov): 12148-60.

    Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo.
    Bissell MJ
    Cancer research 66.3 (2006 Feb 1): 1526-35.

    Chondrocyte culture in three dimensional alginate sulfate hydrogels promotes proliferation while maintaining expression of chondrogenic markers.
    Zenobi-Wong M
    Tissue engineering. Part A 20.9-10 (2014 May): 1454-64.

    Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions.
    Haga H
    Experimental cell research 319.19 (2013 Nov 15): 2916-27.

    Beta 1 integrin binding plays a role in the constant traction force generation in response to varying stiffness for cells grown on mature cardiac extracellular matrix.
    Black LD 3rd
    Experimental cell research 330.2 (2015 Jan 15): 311-24.

    Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2.
    Schmaier AH
    American journal of physiology. Heart and circulatory physiology 305.3 (2013 Aug 1): H305-20.

    A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system.
    Kwok T
    Cellular microbiology 15.4 (2013 Apr): 554-70.

    Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells.
    Wedlich-Soldner R
    The Journal of cell biology 207.1 (2014 Oct 13): 107-21.

    A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II.
    Wewer UM
    Molecular and cellular biology 32.10 (2012 May): 1788-804.

    Inhibition of tissue factor signaling suppresses tumor growth.
    Ruf W
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