H5A4
Catalog Fields
Clone ID/Product Name: H5A4
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: ITGAM
Ab Isotype: MIgG1
Gene Name:
Entrez Gene ID: 3684
Clonality: Monoclonal
Immunogen: Adult Human adherent spleen cells
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: P3X653-Ag8
Epitope Mapped: No
Antigen Name: CD11b (Integrin alpha-M, Mac-1 alpha chain), human
Epitope Location or Sequence:
Alternate Antigen Name:
Deposit Date: 4/12/1993
Antigen Molecular Weight: Predicted: 127 kDa; Apparent: 170 kDa
Depositor: August, J.T. / Hildreth, J.E.K.
Antigen Sequence:
Depositor Institution: Johns Hopkins University School of Medicine
Antigen Species: Human
Depositor Notes: Does not work on pig. Blocks leukocyte adhesion and inhibits T cell activity; no effect on NK cell activity. Stains frozen sections of human tonsil. Binds to PBMC.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Human
Additional Information: Mac-1 is a macrophage differenciation antigen and a marker for microglia.
Recommended Applications: ELISA, FACS, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot