Antibody Name: MW7
Antigen:huntingtin
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgM
Myeloma Strain: HL-1
Antibody Registry / RRID: AB_528296
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Recombinant Hd exon-1 67Q aggregate
Immunogen Sequence: Partial protein
Epitope Mapped: Yes
Epitope Location / Seq: N-terminal, polyP
Clone: —
Additional Info: Western blot: in Human, weak binding to high molecular weight Htt, and strong binding to two smaller protein bands (doesn't differentiate between HD and non-HD); in mice, preferential strong binding to expanded polyQ domain. ICC: perinuclear or nuclear membranes in WT and expanded polyQ domain mutant; stains aggregates as inclusions in the nuclei of expanded polyQ domain mutant.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human, Mouse
Predicted Reactivity: —
Depositor
Depositor Name: P.H. Patterson
Institution: California Institute of Technology
Deposit Date: January 23, 2003
Depositor Notes: —
Recommended Applications
ELISA
Function Blocking
IF
IHC
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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