MW7
Catalog Fields
Clone ID/Product Name: MW7
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: HTT
Ab Isotype: MIgM
Gene Name:
Entrez Gene ID: 3064
Clonality: Monoclonal
Immunogen: Recombinant Hd exon-1 67Q aggregate
Clone:
Immunogen Sequence: Partial protein
Myeloma Strain: HL-1
Epitope Mapped: Yes
Antigen Name: huntingtin
Epitope Location or Sequence: N-terminal, polyP
Alternate Antigen Name:
Deposit Date: 1/23/2003
Antigen Molecular Weight: Apparent: 348 kDa
Depositor: Patterson, P.H.
Antigen Sequence:
Depositor Institution: California Institute of Technology
Antigen Species: Human
Depositor Notes:
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Human, Mouse
Additional Information: Western blot: in Human, weak binding to high molecular weight Htt, and strong binding to two smaller protein bands (doesn't differentiate between HD and non-HD); in mice, preferential strong binding to expanded polyQ domain. ICC: perinuclear or nuclear membranes in WT and expanded polyQ domain mutant; stains aggregates as inclusions in the nuclei of expanded polyQ domain mutant.
Recommended Applications: ELISA, Function Blocking, Immunofluorescence, Immunohistochemistry, Western Blot