Antibody Name: MW8
Antigen:Huntingtin
Sagittal striatal sections in HdhQ150 mice aged 12 months using DSHB antibody immunostained with DSHB antibody MW8 anti-Huntingtin. PMID: 31282030, Fig. 2F.
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG2a
Myeloma Strain: HL-1
Antibody Registry / RRID: AB_528297
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Hd exon-1 67Q aggregate
Immunogen Sequence: HDx-67Q
Epitope Mapped: Yes
Epitope Location / Seq: AEEPLHRPK/ a.a. 83-90
Clone: —
Additional Info: RRID:AB_528297; Time-resolved Förster resonance energy transfer (TR-FRET) assay has been developed using MW8 to assay huntingtin aggregates. PMID: 22365609 22984513
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human, Mouse
Predicted Reactivity: —
Depositor
Depositor Name: P.H. Patterson
Institution: California Institute of Technology
Deposit Date: January 23, 2003
Depositor Notes: The MW8 exclusively stains aggregates as inclusions in both nuclei and in the neuropil. This antigen is also known as huntington disease protein.
Recommended Applications
ELISA
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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