Clone ID / Name: 8C2
Anti - cadherin, E-
Immunofluorescent image of a Xenopus laevis embryo head labeled with DSHB antibody 8C2 against E-cadherin. Image Credit: Lisa Lansdon
Catalog Fields
Identity
Clone ID / Name: 8C2
Alternate Antibody Name: —
Antigen Name: cadherin, E-
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: cdh1
Entrez Gene ID: 100337618
Antigen Sequence: —
Antigen Species: Xenopus
Antigen Mol. Weight: Predicted: 79 kDa (mature E-cadherin); Apparent: 140 kDa
Uniprot ID: P30944
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: sp-2/0
Antibody Registry / RRID: AB_528117
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Purified E-cadherin extracellular domain (100 kDa trypsin fragment ectodomain) from Xenopus A6 kidney cell line.
Immunogen Sequence: partial protein
Epitope Mapped: Yes
Epitope Location / Seq: Extracellular domain
Clone: —
Additional Info: —
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Avian, Xenopus
Predicted Reactivity: —
Depositor
Depositor Name: B.M. Gumbiner
Institution: University of Virginia
Deposit Date: May 7, 1993
Depositor Notes: 8C2 only binds the -(Ca++) conformation of E-cadherin. Blocks epithelial cell-cell adhesion and cell junction formation. Stains ectoderm, all epithelia and regions of cell-cell contact. E-cadherin-specific by immunoblotting and immunoprecipitation.
Recommended Applications
Function Blocking
IF
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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