IIH6 C4
Catalog Fields
Clone ID/Product Name: IIH6 C4
Available to For-Profits: Yes
Alternate Antibody Name: IIH6
Gene Symbol: DAG1
Ab Isotype: MIgM, kappa light chain
Gene Name:
Antibody Registry ID: AB_2617216
Uniprot ID: Q28685
Entrez Gene ID: 100009278
Clonality: Monoclonal
Immunogen: Dystrophin complex isolated from detergent-solubilized skeletal muscle membranes using wheat-germ agglutinin-Sepharose.
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: P3X63Ag8.653
Epitope Mapped: Yes
Antigen Name: Dystroglycan, alpha
Epitope Location or Sequence: N-terminal region (lamiminin-binding glycoepitope)
Alternate Antigen Name:
Deposit Date: 9/29/2011
Antigen Molecular Weight: Apparent: 156 kDa
Depositor: Campbell, K.P.
Antigen Sequence:
Depositor Institution: University of Iowa
Antigen Species: Rabbit
Depositor Notes: This antibody binds to an extracellular peripheral glycoprotein that is associated with beta-dystroglycan, a transmembrane protein.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): No
Confirmed Species Reactivity: Canine, Human, Mouse, Rabbit, Rat
Additional Information: IIH6 C4 recognizes a glycoconjugate on the LARGE fully glycosylated form of alpha DAG. It detects the laminin-binding glycoepitope. Dystroglycan is a central component of the dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. RRID:AB_2617216
Recommended Applications: FACS, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot