Clone ID / Name: IIH6 C4
Anti - Dystroglycan, alpha
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgM, kappa light chain
Myeloma Strain: P3X63Ag8.653
Antibody Registry / RRID: AB_2617216
Available to For-Profits: Yes
Hybridoma Available: No
Immunogen & Epitope
Immunogen: Dystrophin complex isolated from detergent-solubilized skeletal muscle membranes using wheat-germ agglutinin-Sepharose.
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: N-terminal region (lamiminin-binding glycoepitope)
Clone: —
Additional Info: IIH6 C4 recognizes a glycoconjugate on the LARGE fully glycosylated form of alpha DAG. It detects the laminin-binding glycoepitope. Dystroglycan is a central component of the dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. RRID:AB_2617216
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Canine, Human, Mouse, Rabbit, Rat
Predicted Reactivity: —
Depositor
Depositor Name: K.P. Campbell
Institution: University of Iowa
Deposit Date: September 29, 2011
Depositor Notes: This antibody binds to an extracellular peripheral glycoprotein that is associated with beta-dystroglycan, a transmembrane protein.
Recommended Applications
FACS
Function Blocking
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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