Clone ID / Name: CIIC1
Anti - collagen type II
Immunofluorescent image of mouse ear cartilage scaffolds labeled with DSHB antibody CIIC1 against collagen type II (red). Image Credit: Roman Krawetz. PMID: 30305302, Fig. 5L.
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: MIgG2a, kappa light chain
Myeloma Strain: X63.Ag8.653
Antibody Registry / RRID: AB_528164
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: native chick type I1 collagen
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: The ARGLT epitope is located at aa 359-363 of the human collagen II triple helical region
Clone: —
Additional Info: The CIIC1 antibody induces sub clinical arthritis if injected at low (0.5 mg) doses and clinical arthritis in mice if injected at higher doses and in combination with other antibodies (see [PMID: 16125192]).
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Bovine, Chick, Fish, Human, Mouse, Ovine, Rabbit, Rat, Xenopus
Predicted Reactivity: —
Depositor
Depositor Name: R. Holmdahl / K. Rubin
Institution: University of Uppsala
Deposit Date: August 31, 1989
Depositor Notes: Stains hyaluronidase-treated fetal and adult mouse and human cartilage in vitro as well as mouse cartilage in vivo. This antibody recognizes native triple-helical type II collagen. It does not bind to denatured type II collagen (PMID: 25005029).
Recommended Applications
ELISA
IF
IHC
WB
Each lab must optimize concentration per application and species. Full usage recommendations →