Clone ID / Name: H4B4
Anti - LAMP-2 (human)
Immunofluorescent confocal microscope image of a KTC-Z cell labeled with DSHB antibody H4B4 against LAMP2 (red). PMID: 34208608, Fig. 6B'.
Catalog Fields
Identity
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: P3X653-Ag8
Antibody Registry / RRID: AB_528129
Available to For-Profits: Yes
Hybridoma Available: No
Immunogen & Epitope
Immunogen: Human adherent peripheral blood cells
Immunogen Sequence: Full length protein
Epitope Mapped: Yes
Epitope Location / Seq: Luminal region of LAMP-2
Clone: —
Additional Info: LAMP2 is a marker of lysosmes and late endosomes. H4B4 has been reported to recognize all three LAMP-2 isoforms A, B, and C [PMID: 22365987], suggesting that the epitope is located on the luminal region of LAMP-2 common to all isoforms. This antibody induces apoptosis of human microvascular endothelium in vitro [PMID: 18836458].
RRID:AB_528129
RRID:AB_528129
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Human
Predicted Reactivity: —
Depositor
Depositor Name: J.T. August / J.E.K. Hildreth
Institution: Johns Hopkins University School of Medicine
Deposit Date: April 12, 1993
Depositor Notes: Fusion: 1983
Recommended Applications
FACS
Function Blocking
IF
IHC
IP
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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