H4B4
Catalog Fields
Clone ID/Product Name: H4B4
Available to For-Profits: Yes
Alternate Antibody Name: CD107b
Gene Symbol: LAMP2
Ab Isotype: MIgG1
Gene Name:
Entrez Gene ID: 3920
Clonality: Monoclonal
Immunogen: Human adherent peripheral blood cells
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: P3X653-Ag8
Epitope Mapped: Yes
Antigen Name: LAMP-2 (human)
Epitope Location or Sequence: Luminal region of LAMP-2
Alternate Antigen Name:
Deposit Date: 4/12/1993
Antigen Molecular Weight: Predicted: 42 kDa; Apparent: 120 kDa
Depositor: August, J.T. / Hildreth, J.E.K.
Antigen Sequence:
Depositor Institution: Johns Hopkins University School of Medicine
Antigen Species: Human
Depositor Notes: Fusion: 1983
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): No
Confirmed Species Reactivity: Human
Additional Information: LAMP2 is a marker of lysosmes and late endosomes. H4B4 has been reported to recognize all three LAMP-2 isoforms A, B, and C [PMID: 22365987], suggesting that the epitope is located on the luminal region of LAMP-2 common to all isoforms. This antibody induces apoptosis of human microvascular endothelium in vitro [PMID: 18836458].
RRID:AB_528129
RRID:AB_528129
Recommended Applications: FACS, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot