Antibody Name: PY654-B-catenin
Antigen:catenin, beta- (MIgM)
Catalog Fields
Identity
Clone ID / Antibody Name: PY654-B-catenin
Alternate Antibody Name: PY654
Antigen Name: catenin, beta- (MIgM)
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: Ctnnb1
Entrez Gene ID: 12387
Antigen Sequence: —
Antigen Species: mouse
Antigen Mol. Weight: Predicted: 85 kDa
Uniprot ID: Q02248
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgM
Myeloma Strain: SP2/0
Antibody Registry / RRID: AB_10144656
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: syntetic phospho-peptide
Immunogen Sequence: NH2-CELLHSRNEGVATpYAA-OH
Epitope Mapped: Yes
Epitope Location / Seq: NH2-CELLHSRNEGVATpYAA-OH
Clone: —
Additional Info: This antibody is specific to beta-catenin phosphorylated at Tyr 654. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y654F beta-catenin. See mAb PY489-B-catenin for an antibody specific to beta-catenin phosphorylated at Tyr 489. The catenin target of PY489-B-catenin has been described as nuclear-bound, and the target of PY654-B-catenin has been described as membrane-bound/cytoplasmic [PMID 25367124].
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Chicken, Mouse, Xenopus
Predicted Reactivity: Human
Depositor
Depositor Name: J. Balsamo / J. Lilien
Institution: University of Iowa
Deposit Date: August 11, 2006
Depositor Notes: —
Recommended Applications
IF
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
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