Antibody Name: PY489-B-catenin

Antigen:catenin, beta-

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$50.00

Quantity	Price

SKU: PY489-B-catenin

Product Form :

Supernatant 1.0 ml

~ 13 – 29 μg/mL

Frozen Cells 1 vial

N/A

Growing Cells 1 vial

N/A

iConcentration varies between lots. Lots are distributed in the order they are produced.

In Stock

Available: 1

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Concerns have been raised about the specificity of this antibody. Placed orders imply acceptance of these concerns. For more information, please contact dshb-antibody-help@uiowa.edu.

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Catalog Fields

Identity

Clone ID / Antibody Name: PY489-B-catenin

Alternate Antibody Name: PY489

Antigen Name: catenin, beta-

Alternate Antigen Name: —

Gene Symbol: —

Gene Name: Ctnnb1

Entrez Gene ID: 12387

Antigen Sequence: —

Antigen Species: Mouse

Antigen Mol. Weight: Predicted: 85kDa

Uniprot ID: Q02248

Human Protein Atlas: —

Antibody Properties

Host Species: Mouse

Clonality: Monoclonal

Isotype: Mouse IgM

Myeloma Strain: SP2/0

Antibody Registry / RRID: AB_10144551

Available to For-Profits: Yes

Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.

Immunogen & Epitope

Immunogen: synthetic phospho-peptide

Immunogen Sequence: NH2-CRHQEAEMAQNAVRLHpYGL-OH

Epitope Mapped: Yes

Epitope Location / Seq: NH2-CRHQEAEMAQNAVRLHpYGL-OH

Clone: —

Additional Info: This antibody is specific to beta-catenin phosphorylated at Tyr 489. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y489F beta-catenin. See mAb PY654-B-catenin (IgG) for an antibody specific to beta-catenin phosphorylated at Tyr 654. The catenin target of PY489-B-catenin has been described as nuclear-bound/active beta-catenin, and the target of PY654-B-catenin (IgG) has been described as membrane-bound/cytoplasmic beta-catenin.

Add. Characterization: —

Species Reactivity

Confirmed Reactivity: Canine, Chicken, Mouse

Predicted Reactivity: Human

Depositor

Depositor Name: J. Balsamo / J. Lilien

Institution: University of Iowa

Deposit Date: June 28, 2007

Depositor Notes: Fusion: 09/05.

Recommended Applications

FFPE

IHC

Each lab must optimize concentration per application and species. Full usage recommendations →

UniProt DataUniProtQ02248 ↗

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Could not load UniProt data for Q02248

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Antibody Name: PY489-B-catenin

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