PY654-B-catenin (IgG)
Catalog Fields
Clone ID/Product Name: PY654-B-catenin (IgG)
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: Ctnnb1
Ab Isotype: MIgG1
Gene Name:
Antibody Registry ID: AB_2088265 AB_1157889
Uniprot ID: Q02248
Entrez Gene ID: 12387
Clonality: Monoclonal
Immunogen: synthetic phospho-peptide
Clone:
Immunogen Sequence: NH2-CELLHSRNEGVATpYAA-OH
Myeloma Strain: SP2/0
Epitope Mapped: Yes
Antigen Name: catenin, beta-
Epitope Location or Sequence: NH2-TELLHSRNEGVATpYAA-OH
Alternate Antigen Name:
Deposit Date: 6/28/2007
Antigen Molecular Weight: Predicted: 85kDa
Depositor: Balsamo, J. / Lilien, J.
Antigen Sequence:
Depositor Institution: University of Iowa
Antigen Species: Mouse
Depositor Notes: Fusion: 09/05.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: African green monkey, Chicken, Mouse, Rat
Additional Information: This antibody is specific to beta-catenin phosphorylated at Tyr 654. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y654F beta-catenin. See mAb PY489-B-catenin for an antibody specific to beta-catenin phosphorylated at Tyr 489. The catenin target of PY489-B-catenin has been described as nuclear-bound, and the target of PY654-B-catenin (IgG) has been described as membrane-bound/cytoplasmic [PMID 25367124].
Recommended Applications: Immunofluorescence, Immunoprecipitation, Western Blot