Clone ID / Name: CH1

Anti - Tropomyosin, alpha-1 chain (striated muscle)

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$50.00

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SKU: CH1

Product Form :

Supernatant 1.0 ml

~ 35 – 40 μg/mL

Frozen Cells 1 vial

N/A

Growing Cells 1 vial

N/A

iConcentration varies between lots. Lots are distributed in the order they are produced.

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Available: 1

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Catalog Fields

Identity

Clone ID / Name: CH1

Alternate Antibody Name: —

Antigen Name: Tropomyosin, alpha-1 chain (striated muscle)

Alternate Antigen Name: —

Gene Symbol: —

Gene Name: TPM1

Entrez Gene ID: 396366

Antigen Sequence: —

Antigen Species: Chicken

Antigen Mol. Weight: Apparent: 39 kDa (or smaller depending on the isoform)

Uniprot ID: P04268

Human Protein Atlas: —

Antibody Properties

Host Species: Mouse

Clonality: Monoclonal

Isotype: Mouse IgG1

Myeloma Strain: NS1

Antibody Registry / RRID: AB_2205770

Available to For-Profits: Yes

Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.

Immunogen & Epitope

Immunogen: Purified chicken cardiac muscle tropomyosin

Immunogen Sequence: Full length protein

Epitope Mapped: Yes

Epitope Location / Seq: CH1 has been reported to bind to the peptide region encoded by exon 9a of TPM genes [PMID: 24958154]; this exon is well conserved in all vertebrates. But, the binding of CH1 has also been described to be limited to alpha9a [PMID: 22069507].

Clone: —

Additional Info: CH1 reacts strongly with striated muscle forms of tropomyosin, including cardiac alpha-tropomyosin and skeletal alpha- and beta-tropomyosins, but not with tropomyosin isoforms from gizzard (smooth muscle) or chicken embryo fibroblasts. CH1 interferes with the binding of tropomyosin to actin. CH1 recognizes sarcomeric Tm soforms alpha-fast, beta, and alpha-slow with poor affinity for alpha-slow.

Add. Characterization: —

Species Reactivity

Confirmed Reactivity: Axolotl, Broad species, Chicken, Fish, Human, Mouse, Rat, Xenopus, Zebrafish

Predicted Reactivity: —

Depositor

Depositor Name: J.J.-C. Lin

Institution: University of Iowa

Deposit Date: September 8, 1988

Depositor Notes: —

Recommended Applications

ELISA

FFPE

Function Blocking

Each lab must optimize concentration per application and species. Full usage recommendations →

UniProt DataUniProtP04268 ↗

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Could not load UniProt data for P04268

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Clone ID / Name: CH1

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