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Rat-Elav-7E8A10 anti-elav

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$40.00
SKU: Rat-Elav-7E8A10 anti-elav
View product citations for antibody Rat-Elav-7E8A10 anti-elav on CiteAb

In Stock

Available: 165

DSHB Data Sheet

Catalog Fields

Antigen: elav Drosophila protein; embryonic lethal abnormal vision
Hybridoma Cells Available: Yes
Antigen Species: Drosophila
Depositor: Rubin, G.M.
Isotype: RIgG2a
Depositors Institution: HHMI / Janelia Farm Research
Host Species: rat
Depositors Notes: This antibody is a marker for most differentiated neuronal cells in the central and peripheral nervous system.
Positive Tested Species Reactivity: Drosophila
Gene: elav
Antigen Molecular Weight: 50.8 kD Predicted
Alternate Gene Names: elav-2, elav-3, fliJ, weg
Immunogen: Recombinant protein
Clonality: Monoclonal
Uniprot ID: P16914 
Epitope Mapped: No
Entrez Gene ID: 31000 
Immunogen Sequence: Full length protein
Antibody Registry ID: AB_528218 
Recommended Applications: Immunofluorescence, Immunohistochemistry
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
Rat-Elav-7E8A10 anti-elav was deposited to the DSHB by Rubin, G.M. (DSHB Hybridoma Product Rat-Elav-7E8A10 anti-elav)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. To ensure retention of antibody activity, we recommend aliquotting the product into two parts: 1) a volume of antibody stored at 4°C to be used within two weeks. 2) the remaining product diluted with an equal volume of molecular grade glycerol and stored at -20°C.
Usage Recommendations
While optimal Ig concentration for an application will vary, a good starting concentration for immunohistochemistry (IHC), immunofluorescence(IF) and staining is 2-5 µg/ml. For Western blots, the concentration is decreased by one order of magnitude (that is, 0.2-0.5 µg/ml).
All cell products contain the antimicrobial ProClin. Click here for additional information.

39 References

  • Initial Publication
  • IF References
  • IHC References
  • All References
  • Initial Publication
    IF References

    Split ends antagonizes the Notch and potentiates the EGFR signaling pathways during Drosophila eye development.
    Rebay I
    Mechanisms of development 124.9-10 (2007 Sep-Oct): 792-806.

    Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
    Bellen HJ
    PLoS genetics 12.5 (2016 May): e1006054.

    dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis.
    Janody F
    PLoS genetics 12.7 (2016 Jul): e1006204.

    Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye.
    Pignoni F
    Developmental biology 421.1 (2017 Jan 1): 67-76.

    Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster.
    Kamikouchi A
    The Journal of comparative neurology 524.6 (2016 Apr 15): 1099-164.

    Polycomb group (PcG) proteins and Pax6 cooperate to inhibit <i>in vivo</i> reprogramming of the developing <i>Drosophila</i> eye.
    Kumar JP
    Development (Cambridge, England) 145.7 (2018 Apr 4): .

    Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation.
    Zelhof AC
    Developmental biology 414.1 (2016 Jun 1): 4-20.

    14-3-3 proteins regulate Tctp-Rheb interaction for organ growth in Drosophila.
    Choi KW
    Nature communications 7. (2016 May 6): 11501.

    Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation.
    Singh B
    The Journal of biological chemistry 291.12 (2016 Mar 18): 6200-17.

    Tao Negatively Regulates BMP Signaling During Neuromuscular Junction Development in Drosophila.
    Vanderzalm PJ
    Developmental neurobiology 79.4 (2019 Apr): 335-349.

    De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia.
    Malicdan MCV
    American journal of human genetics 105.2 (2019 Aug 1): 413-424.

    A circuit-dependent ROS feedback loop mediates glutamate excitotoxicity to sculpt the <i>Drosophila</i> motor system.
    Yao CK
    eLife 8. (2019 Jul 18): .

    IHC References

    Ecdysone-dependent and ecdysone-independent programmed cell death in the developing optic lobe of Drosophila.
    Tsujimura H
    Developmental biology 374.1 (2013 Feb 1): 127-41.

    The Gcm/Glide molecular and cellular pathway: new actors and new lineages.
    Giangrande A
    Developmental biology 375.1 (2013 Mar 1): 65-78.

    Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag.
    McCabe BD
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.20 (2012 May 16): 7058-73.

    The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis.
    Luo L
    Cell 141.3 (2010 Apr 30): 536-48.

    Notch and Prospero repress proliferation following cyclin E overexpression in the Drosophila bristle lineage.
    Audibert A
    PLoS genetics 5.8 (2009 Aug): e1000594.

    Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster.
    Martinez JD
    Cell division 3. (2008 Jan 14): 2.

    Photoreceptor neurons find new synaptic targets when misdirected by overexpressing runt in Drosophila.
    Meinertzhagen IA
    The Journal of neuroscience : the official journal of the Society for Neuroscience 29.3 (2009 Jan 21): 828-41.

    Split ends antagonizes the Notch and potentiates the EGFR signaling pathways during Drosophila eye development.
    Rebay I
    Mechanisms of development 124.9-10 (2007 Sep-Oct): 792-806.

    Development of morphological diversity of dendrites in Drosophila by the BTB-zinc finger protein abrupt.
    Uemura T
    Neuron 43.6 (2004 Sep 16): 809-22.

    Scabrous and Gp150 are endosomal proteins that regulate Notch activity.
    Baker NE
    Development (Cambridge, England) 130.13 (2003 Jul): 2819-27.

    Notch activity in neural cells triggered by a mutant allele with altered glycosylation.
    Baker NE
    Development (Cambridge, England) 130.13 (2003 Jul): 2829-40.

    Immunohistochemical study of Ca2+/calmodulin-dependent protein kinase II in the Drosophila brain using a specific monoclonal antibody.
    Ohsako S
    Brain research 974.1-2 (2003 Jun 6): 99-116.

    Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye.
    Baker NE
    Developmental cell 4.3 (2003 Mar): 359-69.

    Regulation of notch signaling by o-linked fucose.
    Irvine KD
    Cell 111.6 (2002 Dec 13): 893-904.

    The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye.
    Yu SY
    Cell 104.5 (2001 Mar 9): 699-708.

    Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye.
    Baker NE
    Current biology : CB 11.5 (2001 Mar 6): 330-8.

    Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila.
    Preiss A
    Mechanisms of development 94.1-2 (2000 Jun): 3-12.

    Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila.
    Preiss A
    Mechanisms of development 94.1-2 (2000 Jun): 3-12.

    Notchspl is deficient for inductive processes in the eye, and E(spl)D enhances split by interfering with proneural activity.
    Preiss A
    Developmental biology 208.2 (1999 Apr 15): 406-15.

    Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster.
    Ito K
    The Journal of comparative neurology 499.3 (2006 Nov 20): 317-56.

    Neural architecture of the primary gustatory center of Drosophila melanogaster visualized with GAL4 and LexA enhancer-trap systems.
    Ito K
    The Journal of comparative neurology 518.20 (2010 Oct 15): 4147-81.

    Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.
    Saigo K
    Development (Cambridge, England) 127.7 (2000 Apr): 1531-40.

    Increased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.
    Barber DL
    eLife 4. (2015 Mar 20): .

    Dendritic diversification through transcription factor-mediated suppression of alternative morphologies.
    Grueber WB
    Development (Cambridge, England) 143.8 (2016 Apr 15): 1351-62.

    A multiplexable TALE-based binary expression system for in vivo cellular interaction studies.
    Fulga TA
    Nature communications 8.1 (2017 Nov 21): 1663.

    cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
    Shulman JM
    Cell reports 28.7 (2019 Aug 13): 1799-1813.e5.

    Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix.
    Mlodzik M
    Open biology 9.8 (2019 Aug 30): 190148.

    Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs.
    Hassan BA
    Developmental cell 50.6 (2019 Sep 23): 780-792.e7.

    All References

    Ecdysone-dependent and ecdysone-independent programmed cell death in the developing optic lobe of Drosophila.
    Tsujimura H
    Developmental biology 374.1 (2013 Feb 1): 127-41.

    The Gcm/Glide molecular and cellular pathway: new actors and new lineages.
    Giangrande A
    Developmental biology 375.1 (2013 Mar 1): 65-78.

    Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag.
    McCabe BD
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.20 (2012 May 16): 7058-73.

    The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis.
    Luo L
    Cell 141.3 (2010 Apr 30): 536-48.

    Notch and Prospero repress proliferation following cyclin E overexpression in the Drosophila bristle lineage.
    Audibert A
    PLoS genetics 5.8 (2009 Aug): e1000594.

    Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster.
    Martinez JD
    Cell division 3. (2008 Jan 14): 2.

    Photoreceptor neurons find new synaptic targets when misdirected by overexpressing runt in Drosophila.
    Meinertzhagen IA
    The Journal of neuroscience : the official journal of the Society for Neuroscience 29.3 (2009 Jan 21): 828-41.

    Split ends antagonizes the Notch and potentiates the EGFR signaling pathways during Drosophila eye development.
    Rebay I
    Mechanisms of development 124.9-10 (2007 Sep-Oct): 792-806.

    Development of morphological diversity of dendrites in Drosophila by the BTB-zinc finger protein abrupt.
    Uemura T
    Neuron 43.6 (2004 Sep 16): 809-22.

    Scabrous and Gp150 are endosomal proteins that regulate Notch activity.
    Baker NE
    Development (Cambridge, England) 130.13 (2003 Jul): 2819-27.

    Notch activity in neural cells triggered by a mutant allele with altered glycosylation.
    Baker NE
    Development (Cambridge, England) 130.13 (2003 Jul): 2829-40.

    Immunohistochemical study of Ca2+/calmodulin-dependent protein kinase II in the Drosophila brain using a specific monoclonal antibody.
    Ohsako S
    Brain research 974.1-2 (2003 Jun 6): 99-116.

    Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye.
    Baker NE
    Developmental cell 4.3 (2003 Mar): 359-69.

    Regulation of notch signaling by o-linked fucose.
    Irvine KD
    Cell 111.6 (2002 Dec 13): 893-904.

    The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye.
    Yu SY
    Cell 104.5 (2001 Mar 9): 699-708.

    Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye.
    Baker NE
    Current biology : CB 11.5 (2001 Mar 6): 330-8.

    Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila.
    Preiss A
    Mechanisms of development 94.1-2 (2000 Jun): 3-12.

    Notchspl is deficient for inductive processes in the eye, and E(spl)D enhances split by interfering with proneural activity.
    Preiss A
    Developmental biology 208.2 (1999 Apr 15): 406-15.

    Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster.
    Ito K
    The Journal of comparative neurology 499.3 (2006 Nov 20): 317-56.

    Neural architecture of the primary gustatory center of Drosophila melanogaster visualized with GAL4 and LexA enhancer-trap systems.
    Ito K
    The Journal of comparative neurology 518.20 (2010 Oct 15): 4147-81.

    Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.
    Saigo K
    Development (Cambridge, England) 127.7 (2000 Apr): 1531-40.

    Increased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.
    Barber DL
    eLife 4. (2015 Mar 20): .

    Dendritic diversification through transcription factor-mediated suppression of alternative morphologies.
    Grueber WB
    Development (Cambridge, England) 143.8 (2016 Apr 15): 1351-62.

    A multiplexable TALE-based binary expression system for in vivo cellular interaction studies.
    Fulga TA
    Nature communications 8.1 (2017 Nov 21): 1663.

    cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
    Shulman JM
    Cell reports 28.7 (2019 Aug 13): 1799-1813.e5.

    Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix.
    Mlodzik M
    Open biology 9.8 (2019 Aug 30): 190148.

    Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs.
    Hassan BA
    Developmental cell 50.6 (2019 Sep 23): 780-792.e7.

    Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
    Bellen HJ
    PLoS genetics 12.5 (2016 May): e1006054.

    dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis.
    Janody F
    PLoS genetics 12.7 (2016 Jul): e1006204.

    Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye.
    Pignoni F
    Developmental biology 421.1 (2017 Jan 1): 67-76.

    Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster.
    Kamikouchi A
    The Journal of comparative neurology 524.6 (2016 Apr 15): 1099-164.

    Polycomb group (PcG) proteins and Pax6 cooperate to inhibit <i>in vivo</i> reprogramming of the developing <i>Drosophila</i> eye.
    Kumar JP
    Development (Cambridge, England) 145.7 (2018 Apr 4): .

    Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation.
    Zelhof AC
    Developmental biology 414.1 (2016 Jun 1): 4-20.

    14-3-3 proteins regulate Tctp-Rheb interaction for organ growth in Drosophila.
    Choi KW
    Nature communications 7. (2016 May 6): 11501.

    Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation.
    Singh B
    The Journal of biological chemistry 291.12 (2016 Mar 18): 6200-17.

    Tao Negatively Regulates BMP Signaling During Neuromuscular Junction Development in Drosophila.
    Vanderzalm PJ
    Developmental neurobiology 79.4 (2019 Apr): 335-349.

    De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia.
    Malicdan MCV
    American journal of human genetics 105.2 (2019 Aug 1): 413-424.

    A circuit-dependent ROS feedback loop mediates glutamate excitotoxicity to sculpt the <i>Drosophila</i> motor system.
    Yao CK
    eLife 8. (2019 Jul 18): .

    The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway.
    Rubin GM
    Cell 78.1 (1994 Jul 15): 137-47.

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