Clone ID / Name: F461.3B
Anti - Notch, extracellular domain, EGF repeats #5-7
Catalog Fields
Identity
Clone ID / Name: F461.3B
Alternate Antibody Name: —
Antigen Name: Notch, extracellular domain, EGF repeats #5-7
Alternate Antigen Name: —
Gene Symbol: —
Gene Name: N
Entrez Gene ID: 31293
Antigen Sequence: —
Antigen Species: Drosophila
Antigen Mol. Weight: Predicted: 289 kDa; Apparent: 300 kDa and lower MW N-terminal fragment, resulting from proteolysis.
Uniprot ID: P07207
Human Protein Atlas: —
Antibody Properties
Host Species: Mouse
Clonality: Monoclonal
Isotype: Mouse IgG1
Myeloma Strain: Ag8
Antibody Registry / RRID: AB_528409
Available to For-Profits: Yes
Hybridoma Available: Yes
Cell lines cannot be distributed to commercial/for-profit users.
Cell lines cannot be distributed to commercial/for-profit users.
Immunogen & Epitope
Immunogen: Recombinant fusion protein containing the EGF repeats #5-7
Immunogen Sequence: Partial protein
Epitope Mapped: Yes
Epitope Location / Seq: extracellular domain, EGF repeats #5-7 [see depositor notes]
Clone: —
Additional Info: The Neurogenic locus Notch protein functions as a transmembrane receptor for membrane-bound ligands Delta and Serrate to regulate neurodevelopment. Upon ligand activation, the intracellular domain (NICD) is released from the cell membrane, and forms a transcriptional activator complex with the Suppressor of hairless protein.
Add. Characterization: —
Species Reactivity
Confirmed Reactivity: Drosophila
Predicted Reactivity: —
Depositor
Depositor Name: S. Artavanis-Tsakonas
Institution: Harvard Medical School
Deposit Date: May 2, 2000
Depositor Notes: This antibody was generated against the extracellular domain of Notch containing the EGF repeats # 5-7
Recommended Applications
IF
WB
Each lab must optimize concentration per application and species. Full usage recommendations →
▼
Could not load UniProt data for P07207