SUK 4
Catalog Fields
Clone ID/Product Name: SUK 4
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol:
Ab Isotype: MIgG1
Gene Name:
Entrez Gene ID: 373178
Clonality: Monoclonal
Immunogen: Partially purified native kinesin from see urchin egg cytosol
Clone:
Immunogen Sequence: Full length protein
Myeloma Strain: P3x635-68.653
Epitope Mapped: Yes
Antigen Name: kinesin heavy chain, head region
Epitope Location or Sequence: Head region of kinesin heavy chain containing the microtubule-binding region. The epitope is located on aa 336-390 of the Drosophila kinesin heavy chain which corresponds to aa 328-382 of the urchin protein.
Alternate Antigen Name:
Deposit Date: 9/12/1991
Antigen Molecular Weight: Predicted: 118 kDa; Apparent: 130 kDa
Depositor: Scholey, J.M.
Antigen Sequence:
Depositor Institution: University of California, Davis
Antigen Species: Sea Urchin
Depositor Notes: Inhibits sea urchin egg kinesin-induced microtubule translocation. SUK 4 doesn't cross react with squid kinesin.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: Bovine, Canine, Drosophila, Human, Mouse, Planaria, Sea Urchin, Shark, Xenopus
Additional Information: In mice, SUK 4 recognizes the three kinesin-1 KIF5A, KIF5B and KIF5C, with a more intense stainning for KIF5A [PMID: 10964943]. In any publications that result from the use of SUK 2, 4, or 5 antibody, Dr. Jonathan Scholey requests that the following be cited: Ingold, A.L., Cohn, S.A., and Scholey, J.M. (1988). Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains. J. Cell Biol. 107, 2657-3667.
Recommended Applications: Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot