Talin E16B

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$40.00
SKU: Talin E16B
View product citations for antibody Talin E16B on CiteAb

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DSHB Data Sheet

Catalog Fields

Antigen: Talin carboxy terminus 534 amino acids
Hybridoma Cells Available: Yes
Antigen Species: Drosophila
Depositor: White, R.
Isotype: MIgG2b
Antigen Sequence:
Host Species: mouse
Depositors Institution: University of Cambridge
Positive Tested Species Reactivity: Drosophila
Depositors Notes: Recommend use as a cocktail of monoclonal antibodies (A22A plus E16B) for immunohistochemistry.
Antigen Molecular Weight: Multiple isoforms; Predicted (isoform B): 307 kDa
Human Protein Atlas:  
Predicted Species Reactivity:  
Gene: rhea
Immunogen: Recombinant talin, C-terminal (534 amino acids of isoform B)/GST fusion protein
Alternate Gene Names: CG6831, tendrils, Tln, talin
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: Yes
Myeloma Strain: NSO
Epitope Location or Sequence: C-terminal (aa 2302-2836) of isoform B
Uniprot ID: Q9VSL8 
Immunogen Sequence: Partial protein
Entrez Gene ID: 38978 
Additional Characterization:  
Antibody Registry ID: AB_10683995 
Additional Information: This antibody has been suggested to be used in a mix with anti-talin A22A for immunohistochemistry but a number of authors have reported using it alone. This antibody should recognize isoforms B and G and may recognize isoform H, but will not recognize isoforms C or I.
Recommended Applications: Immunofluorescence, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
Talin E16B was deposited to the DSHB by White, R. (DSHB Hybridoma Product Talin E16B)
Storage and Handling Recommendations
Usage Recommendations
All cell products contain the antimicrobial ProClin. Click here for additional information.

12 References

  • Initial Publication
  • IF References
  • WB References
  • Epitope Map References
  • All References
  • Initial Publication

    Talin is essential for integrin function in Drosophila.
    Fristrom JW
    Developmental cell 3.4 (2002 Oct): 569-79.

    IF References

    Talin is essential for integrin function in Drosophila.
    Fristrom JW
    Developmental cell 3.4 (2002 Oct): 569-79.

    Talin is required to position and expand the luminal domain of the Drosophila heart tube.
    Jacobs JR
    Developmental biology 405.2 (2015 Sep 15): 189-201.

    Stage-specific control of niche positioning and integrity in the Drosophila testis.
    Papagiannouli F
    Mechanisms of development 138 Pt 3. (2015 Nov): 336-48.

    Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary.
    McCall K
    Disease models & mechanisms 8.12 (2015 Dec): 1603-14.

    An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton.
    Brown NH
    Nature cell biology 8.6 (2006 Jun): 601-6.

    Integrin-dependent anchoring of a stem-cell niche.
    Brown NH
    Nature cell biology 9.12 (2007 Dec): 1413-8.

    Distinct developmental roles for direct and indirect talin-mediated linkage to actin.
    Tanentzapf G
    Developmental biology 345.1 (2010 Sep 1): 64-77.

    Analysis of integrin turnover in fly myotendinous junctions.
    Tanentzapf G
    Journal of cell science 123.Pt 6 (2010 Mar 15): 939-46.

    Moleskin is essential for the formation of the myotendinous junction in Drosophila.
    Geisbrecht ER
    Developmental biology 359.2 (2011 Nov 15): 176-89.

    The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium.
    Brown NH
    Journal of cell science 122.Pt 23 (2009 Dec 1): 4363-74.

    Drosophila TNF Modulates Tissue Tension in the Embryo to Facilitate Macrophage Invasive Migration.
    Siekhaus DE
    Developmental cell 45.3 (2018 May 7): 331-346.e7.

    Select Septate Junction Proteins Direct ROS-Mediated Paracrine Regulation of Drosophila Cardiac Function.
    Wang W
    Cell reports 28.6 (2019 Aug 6): 1455-1470.e4.

    WB References

    Talin is essential for integrin function in Drosophila.
    Fristrom JW
    Developmental cell 3.4 (2002 Oct): 569-79.

    Talin is required to position and expand the luminal domain of the Drosophila heart tube.
    Jacobs JR
    Developmental biology 405.2 (2015 Sep 15): 189-201.

    Epitope Map References

    Talin is essential for integrin function in Drosophila.
    Fristrom JW
    Developmental cell 3.4 (2002 Oct): 569-79.

    All References

    Talin is essential for integrin function in Drosophila.
    Fristrom JW
    Developmental cell 3.4 (2002 Oct): 569-79.

    Talin is required to position and expand the luminal domain of the Drosophila heart tube.
    Jacobs JR
    Developmental biology 405.2 (2015 Sep 15): 189-201.

    Stage-specific control of niche positioning and integrity in the Drosophila testis.
    Papagiannouli F
    Mechanisms of development 138 Pt 3. (2015 Nov): 336-48.

    Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary.
    McCall K
    Disease models & mechanisms 8.12 (2015 Dec): 1603-14.

    An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton.
    Brown NH
    Nature cell biology 8.6 (2006 Jun): 601-6.

    Integrin-dependent anchoring of a stem-cell niche.
    Brown NH
    Nature cell biology 9.12 (2007 Dec): 1413-8.

    Distinct developmental roles for direct and indirect talin-mediated linkage to actin.
    Tanentzapf G
    Developmental biology 345.1 (2010 Sep 1): 64-77.

    Analysis of integrin turnover in fly myotendinous junctions.
    Tanentzapf G
    Journal of cell science 123.Pt 6 (2010 Mar 15): 939-46.

    Moleskin is essential for the formation of the myotendinous junction in Drosophila.
    Geisbrecht ER
    Developmental biology 359.2 (2011 Nov 15): 176-89.

    The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium.
    Brown NH
    Journal of cell science 122.Pt 23 (2009 Dec 1): 4363-74.

    Drosophila TNF Modulates Tissue Tension in the Embryo to Facilitate Macrophage Invasive Migration.
    Siekhaus DE
    Developmental cell 45.3 (2018 May 7): 331-346.e7.

    Select Septate Junction Proteins Direct ROS-Mediated Paracrine Regulation of Drosophila Cardiac Function.
    Wang W
    Cell reports 28.6 (2019 Aug 6): 1455-1470.e4.

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