TS1.15H

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$40.00
SKU: TS1.15H
View product citations for antibody TS1.15H on CiteAb

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Available: 26

DSHB Data Sheet

Catalog Fields

Antigen: Jagged 1 protein
Hybridoma Cells Available: Yes
Antigen Species: Human
Depositor: Artavanis-Tsakonas, S.
Isotype: MIgG2a
Antigen Sequence:
Host Species: rat
Depositors Institution: Harvard Medical School
Positive Tested Species Reactivity: Human
Depositors Notes:
Antigen Molecular Weight: 134 kDa
Human Protein Atlas:
Predicted Species Reactivity:  
Gene: JAG1
Immunogen: Intracellular domain-GST fusion protein
Alternate Gene Names: AGS, AHD, AWS, CD339, HJ1, JAGL1
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped:
Myeloma Strain: Ag8 cells
Epitope Location or Sequence: Intracellular domain of human jagged1
Uniprot ID: P78504 
Immunogen Sequence: Protein domain
Entrez Gene ID: 182 
Additional Characterization:
Antibody Registry ID: AB_528317 
Additional Information: RRID:AB_528317
Recommended Applications: Immunohistochemistry, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
TS1.15H was deposited to the DSHB by Artavanis-Tsakonas, S. (DSHB Hybridoma Product TS1.15H)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. To ensure retention of antibody activity, we recommend aliquotting the product into two parts: 1) a volume of antibody stored at 4°C to be used within two weeks. 2) the remaining product diluted with an equal volume of molecular grade glycerol and stored at -20°C.
Usage Recommendations
While optimal Ig concentration for an application will vary, a good starting concentration for immunohistochemistry (IHC), immunofluorescence(IF) and staining is 2-5 µg/ml. For Western blots, the concentration is decreased by one order of magnitude (that is, 0.2-0.5 µg/ml).
All cell products contain the antimicrobial ProClin. Click here for additional information.

10 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • FFPE References
  • All References
  • Initial Publication

    Human ligands of the Notch receptor.
    Artavanis-Tsakonas S
    The American journal of pathology 154.3 (1999 Mar): 785-94.

    IF References

    Human ligands of the Notch receptor.
    Artavanis-Tsakonas S
    The American journal of pathology 154.3 (1999 Mar): 785-94.

    Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks.
    McMahon AP
    Developmental cell 23.3 (2012 Sep 11): 637-51.

    Single cell dissection of early kidney development: multilineage priming.
    Potter SS
    Development (Cambridge, England) 141.15 (2014 Aug): 3093-101.

    WB References

    Human ligands of the Notch receptor.
    Artavanis-Tsakonas S
    The American journal of pathology 154.3 (1999 Mar): 785-94.

    Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells.
    Marconi P
    Blood 113.4 (2009 Jan 22): 856-65.

    Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells.
    Foreman KE
    Laboratory investigation; a journal of technical methods and pathology 86.8 (2006 Aug): 842-52.

    Meningioma transcript profiles reveal deregulated Notch signaling pathway.
    Lal A
    Cancer research 65.12 (2005 Jun 15): 5070-5.

    Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.
    Di Ianni M
    European journal of immunology 43.1 (2013 Jan): 182-7.

    The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α.
    Canalis E
    The Journal of biological chemistry 294.39 (2019 Sep 27): 14203-14214.

    IHC References
    FFPE References

    Human ligands of the Notch receptor.
    Artavanis-Tsakonas S
    The American journal of pathology 154.3 (1999 Mar): 785-94.

    All References

    Human ligands of the Notch receptor.
    Artavanis-Tsakonas S
    The American journal of pathology 154.3 (1999 Mar): 785-94.

    Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
    Dörken B
    Blood 99.9 (2002 May 1): 3398-403.

    An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.
    Sham MH
    eLife 6. (2017 Nov 15): .

    Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks.
    McMahon AP
    Developmental cell 23.3 (2012 Sep 11): 637-51.

    Single cell dissection of early kidney development: multilineage priming.
    Potter SS
    Development (Cambridge, England) 141.15 (2014 Aug): 3093-101.

    Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells.
    Marconi P
    Blood 113.4 (2009 Jan 22): 856-65.

    Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells.
    Foreman KE
    Laboratory investigation; a journal of technical methods and pathology 86.8 (2006 Aug): 842-52.

    Meningioma transcript profiles reveal deregulated Notch signaling pathway.
    Lal A
    Cancer research 65.12 (2005 Jun 15): 5070-5.

    Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.
    Di Ianni M
    European journal of immunology 43.1 (2013 Jan): 182-7.

    The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α.
    Canalis E
    The Journal of biological chemistry 294.39 (2019 Sep 27): 14203-14214.

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