mAbdac2-3

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$40.00
SKU: mAbdac2-3
View product citations for antibody mAbdac2-3 on CiteAb

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DSHB Data Sheet

Catalog Fields

Antigen: Dachshund protein
Hybridoma Cells Available: Yes
Antigen Species: Drosophila
Depositor: Rubin, G.M.
Isotype: MIgG1, kappa light chain
Antigen Sequence:
Host Species: mouse
Depositors Institution: University of California at Berkeley
Positive Tested Species Reactivity: Drosophila
Depositors Notes:
Antigen Molecular Weight: 113.6 kDa
Human Protein Atlas:
Predicted Species Reactivity:  
Gene: dac
Immunogen: Recombinant protein domain
Alternate Gene Names: Dmel_CG4952
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped:
Myeloma Strain: P3x63Ag8.653
Epitope Location or Sequence:
Uniprot ID: Q24030 
Immunogen Sequence: a.a. 378-599
Entrez Gene ID: 34982 
Additional Characterization:
Antibody Registry ID: AB_528190 
Additional Information: FBgn0005677. RRID: AB_528190
Recommended Applications: Immunofluorescence, Immunohistochemistry
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
mAbdac2-3 was deposited to the DSHB by Rubin, G.M. (DSHB Hybridoma Product mAbdac2-3)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. To ensure retention of antibody activity, we recommend aliquotting the product into two parts: 1) a volume of antibody stored at 4°C to be used within two weeks. 2) the remaining product diluted with an equal volume of molecular grade glycerol and stored at -20°C.
Usage Recommendations
While optimal Ig concentration for an application will vary, a good starting concentration for immunohistochemistry (IHC), immunofluorescence(IF) and staining is 2-5 µg/ml. For Western blots, the concentration is decreased by one order of magnitude (that is, 0.2-0.5 µg/ml).
All cell products contain the antimicrobial ProClin. Click here for additional information.

26 References

  • Initial Publication
  • IF References
  • IHC References
  • All References
  • Initial Publication

    dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila.
    Rubin GM
    Development (Cambridge, England) 120.12 (1994 Dec): 3473-86.

    IF References

    Proximal to distal cell communication in the Drosophila leg provides a basis for an intercalary mechanism of limb patterning.
    Hayashi S
    Development (Cambridge, England) 126.15 (1999 Aug): 3407-13.

    Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster.
    Beneyto M
    Nature genetics 36.1 (2004 Jan): 31-9.

    Wing-to-Leg homeosis by spineless causes apoptosis regulated by Fish-lips, a novel leucine-rich repeat transmembrane protein.
    Nakato H
    Molecular and cellular biology 25.8 (2005 Apr): 3140-50.

    Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund.
    Mardon G
    Development (Cambridge, England) 132.12 (2005 Jun): 2895-905.

    Direct control of the proneural gene atonal by retinal determination factors during Drosophila eye development.
    Du W
    Developmental biology 313.2 (2008 Jan 15): 787-801.

    Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain.
    O'Connor MB
    Development (Cambridge, England) 135.3 (2008 Feb): 513-21.

    Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT.
    Tabata T
    Development (Cambridge, England) 135.8 (2008 Apr): 1471-80.

    Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning.
    Luo L
    The Journal of neuroscience : the official journal of the Society for Neuroscience 28.24 (2008 Jun 11): 6092-103.

    Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.
    Sawa A
    Molecular psychiatry 13.12 (2008 Dec): 1138-48, 1069.

    Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe.
    Tabata T
    Development (Cambridge, England) 137.19 (2010 Oct): 3193-203.

    Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe.
    Hartenstein V
    Developmental biology 346.2 (2010 Oct 15): 284-95.

    Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development.
    Luo H
    Developmental biology 350.2 (2011 Feb 15): 414-28.

    The Drosophila L1CAM homolog Neuroglian signals through distinct pathways to control different aspects of mushroom body axon development.
    Callaerts P
    Development (Cambridge, England) 138.8 (2011 Apr): 1595-605.

    bantam is required for optic lobe development and glial cell proliferation.
    Padgett RW
    PloS one 7.3 (2012): e32910.

    Replication protein a links cell cycle progression and the onset of neurogenesis in Drosophila optic lobe development.
    Luo H
    The Journal of neuroscience : the official journal of the Society for Neuroscience 33.7 (2013 Feb 13): 2873-88.

    Trehalase regulates neuroepithelial stem cell maintenance and differentiation in the Drosophila optic lobe.
    Luo H
    PloS one 9.7 (2014): e101433.

    Specification of neuronal subtypes by different levels of Hunchback.
    Díaz-Benjumea FJ
    Development (Cambridge, England) 141.22 (2014 Nov): 4366-74.

    A region-specific neurogenesis mode requires migratory progenitors in the Drosophila visual system.
    Salecker I
    Nature neuroscience 18.1 (2015 Jan): 46-55.

    IHC References

    dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila.
    Rubin GM
    Development (Cambridge, England) 120.12 (1994 Dec): 3473-86.

    Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster.
    Beneyto M
    Nature genetics 36.1 (2004 Jan): 31-9.

    Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund.
    Mardon G
    Development (Cambridge, England) 132.12 (2005 Jun): 2895-905.

    The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system.
    Tabata T
    Development (Cambridge, England) 133.5 (2006 Mar): 791-800.

    Mechanisms of TSC-mediated control of synapse assembly and axon guidance.
    Selleck SB
    PloS one 2.4 (2007 Apr 18): e375.

    The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axis.
    Rulifson EJ
    Proceedings of the National Academy of Sciences of the United States of America 104.50 (2007 Dec 11): 19873-8.

    Serial specification of diverse neuroblast identities from a neurogenic placode by Notch and Egfr signaling.
    Rulifson E
    Development (Cambridge, England) 138.14 (2011 Jul): 2883-93.

    Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D.
    Skeath JB
    Developmental biology 388.1 (2014 Apr 1): 117-33.

    The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B.
    Díaz-Benjumea FJ
    Biology open 4.9 (2015 Aug 14): 1132-42.

    An intrinsic mechanism controls reactivation of neural stem cells by spindle matrix proteins.
    Wang H
    Nature communications 8.1 (2017 Jul 25): 122.

    All References

    dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila.
    Rubin GM
    Development (Cambridge, England) 120.12 (1994 Dec): 3473-86.

    Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster.
    Beneyto M
    Nature genetics 36.1 (2004 Jan): 31-9.

    Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund.
    Mardon G
    Development (Cambridge, England) 132.12 (2005 Jun): 2895-905.

    The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system.
    Tabata T
    Development (Cambridge, England) 133.5 (2006 Mar): 791-800.

    Mechanisms of TSC-mediated control of synapse assembly and axon guidance.
    Selleck SB
    PloS one 2.4 (2007 Apr 18): e375.

    The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axis.
    Rulifson EJ
    Proceedings of the National Academy of Sciences of the United States of America 104.50 (2007 Dec 11): 19873-8.

    Serial specification of diverse neuroblast identities from a neurogenic placode by Notch and Egfr signaling.
    Rulifson E
    Development (Cambridge, England) 138.14 (2011 Jul): 2883-93.

    Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D.
    Skeath JB
    Developmental biology 388.1 (2014 Apr 1): 117-33.

    The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B.
    Díaz-Benjumea FJ
    Biology open 4.9 (2015 Aug 14): 1132-42.

    An intrinsic mechanism controls reactivation of neural stem cells by spindle matrix proteins.
    Wang H
    Nature communications 8.1 (2017 Jul 25): 122.

    Proximal to distal cell communication in the Drosophila leg provides a basis for an intercalary mechanism of limb patterning.
    Hayashi S
    Development (Cambridge, England) 126.15 (1999 Aug): 3407-13.

    Wing-to-Leg homeosis by spineless causes apoptosis regulated by Fish-lips, a novel leucine-rich repeat transmembrane protein.
    Nakato H
    Molecular and cellular biology 25.8 (2005 Apr): 3140-50.

    Direct control of the proneural gene atonal by retinal determination factors during Drosophila eye development.
    Du W
    Developmental biology 313.2 (2008 Jan 15): 787-801.

    Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain.
    O'Connor MB
    Development (Cambridge, England) 135.3 (2008 Feb): 513-21.

    Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT.
    Tabata T
    Development (Cambridge, England) 135.8 (2008 Apr): 1471-80.

    Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning.
    Luo L
    The Journal of neuroscience : the official journal of the Society for Neuroscience 28.24 (2008 Jun 11): 6092-103.

    Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.
    Sawa A
    Molecular psychiatry 13.12 (2008 Dec): 1138-48, 1069.

    Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe.
    Tabata T
    Development (Cambridge, England) 137.19 (2010 Oct): 3193-203.

    Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe.
    Hartenstein V
    Developmental biology 346.2 (2010 Oct 15): 284-95.

    Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development.
    Luo H
    Developmental biology 350.2 (2011 Feb 15): 414-28.

    The Drosophila L1CAM homolog Neuroglian signals through distinct pathways to control different aspects of mushroom body axon development.
    Callaerts P
    Development (Cambridge, England) 138.8 (2011 Apr): 1595-605.

    bantam is required for optic lobe development and glial cell proliferation.
    Padgett RW
    PloS one 7.3 (2012): e32910.

    Replication protein a links cell cycle progression and the onset of neurogenesis in Drosophila optic lobe development.
    Luo H
    The Journal of neuroscience : the official journal of the Society for Neuroscience 33.7 (2013 Feb 13): 2873-88.

    Trehalase regulates neuroepithelial stem cell maintenance and differentiation in the Drosophila optic lobe.
    Luo H
    PloS one 9.7 (2014): e101433.

    Specification of neuronal subtypes by different levels of Hunchback.
    Díaz-Benjumea FJ
    Development (Cambridge, England) 141.22 (2014 Nov): 4366-74.

    A region-specific neurogenesis mode requires migratory progenitors in the Drosophila visual system.
    Salecker I
    Nature neuroscience 18.1 (2015 Jan): 46-55.

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