1B1
Catalog Fields
Clone ID/Product Name: 1B1
Available to For-Profits: Yes
Alternate Antibody Name:
Gene Symbol: hts
Ab Isotype: MIgG1
Gene Name:
Entrez Gene ID: 37230
Clonality: Monoclonal
Immunogen: GST-adducin fusion protein expressed in E. coli
Clone:
Immunogen Sequence: aa. 465-903 Of N4 isoform [Uniprot ID Q02645-1]
Myeloma Strain: HL-1
Epitope Mapped: Yes
Antigen Name: Hu-li tai shao, not hts-PC
Epitope Location or Sequence: aa 472-658 of isoform N4 (see additional information)
Alternate Antigen Name:
Deposit Date: 12/2/1997
Antigen Molecular Weight: Multiple molecular weights due to multiple isoforms: the drosophila Adducin-like protein was initially reported to be 87 kDa
Depositor: Lipshitz, H.D.
Antigen Sequence:
Depositor Institution: Hospital for Sick Children
Antigen Species: Drosophila
Depositor Notes: This antigen is also known as adducin-like protein.
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): No
Confirmed Species Reactivity: Drosophila
Additional Information: 1B1 recognizes all isoforms produced by alternative splicing except ShAdd (also known as hts-PC or N32/R2 [Uniprot ID Q02645-3]). By deduction, the 1B1 epitope is located in the region of N4 [Uniprot ID Q02645-1] common to all isoforms but absent in ShAdd, and corresponds to aa 472-658 of isoform N4. 1B1 recognizes only one fragment resulting from proteolysis of Ovhts (N4): Ovhts Fus is recognized but Ovhts-RC is not.
Recommended Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot