LMP1

Catalog Fields
Clone ID/Product Name: LMP1
Available to For-Profits: Yes
Alternate Antibody Name: 2E2
Gene Symbol: LMP-1
Ab Isotype: MIgG2b
Gene Name:
Antibody Registry ID: AB_2161795
Uniprot ID: Q11117
Entrez Gene ID: 180912
Clonality: Monoclonal
Immunogen: Recombinant His6-tagged LMP-1 (N-terminal aa 1-143 of mature LMP-1) fusion protein
Clone:
Immunogen Sequence: Partial protein
Myeloma Strain: P3X63Ag8.653
Epitope Mapped: Yes
Antigen Name: LMP-1
Epitope Location or Sequence: N-terminal aa 1-143 of mature LMP-1
Alternate Antigen Name:
Deposit Date: 2/16/2010
Antigen Molecular Weight: Predicted: 24 kDa; Apparent: 37 kDa
Depositor: Nonet, M.L. / Hadwiger, G. / Dour, S.
Antigen Sequence:
Depositor Institution: Washington University Medical School
Antigen Species: C. elegans
Depositor Notes: Works on C. elegans whole mounts. Stains lysosomes. Specific by western blot: the 37 kDa band observed in wild type is absent from the lmp-1 mutant (nr2045). On whole mount immunostaining, most of the wild type staining is lost in the lmp-1 mutant (nr2045) except that the immunostaining of the nervous system remained in the mutant and became more pronounced, suggesting some cross reaction with another LAMP protein (see initial publication).
Host Species: Mouse
Hybridoma Cells Available (Non-Profit): Yes
Confirmed Species Reactivity: C. elegans
Additional Information: The LAMP family protein lmp-1 is a homolog of the lysosome associated membrane protein family (LAMPs) and is highly expressed and localized to lysosomal-like granules in the C. elegans intestine which can be detected in wild type animals.
Recommended Applications: Immunofluorescence, Western Blot

