Math1 (Atoh1)

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SKU: Math1 (Atoh1)
View product citations for antibody Math1 (Atoh1) on CiteAb

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Available: 52

DSHB Data Sheet

Catalog Fields

Antigen: Math1 (Atoh1)
Hybridoma Cells Available: Yes
Antigen Species: Mouse
Depositor: Johnson, J.
Isotype: MIgG1, kappa light chain
Antigen Sequence:
Host Species: mouse
Depositors Institution: UT Southwestern
Positive Tested Species Reactivity: Mouse
Depositors Notes: Doesn't work on Chicken. Expression in neuronal progenitor cells in dorsal neural tube, EGL of cerebellum, hair cells in inner ear, Merkel cells in skin. Doesn't appear to have a functional effect.
Antigen Molecular Weight: Predicted: 38 kDa
Human Protein Atlas:  
Predicted Species Reactivity:  
Gene: Atoh1
Immunogen: Rcombinant Math1/GST fusion protein
Alternate Gene Names: Ath1
Alternate Antibody Name: Atoh1
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: No
Myeloma Strain:
Epitope Location or Sequence:
Uniprot ID: P48985 
Immunogen Sequence: Full length protein
Entrez Gene ID: 11921 
Additional Characterization:  
Antibody Registry ID: AB_10805299 
Additional Information:
Recommended Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
Math1 (Atoh1) was deposited to the DSHB by Johnson, J. (DSHB Hybridoma Product Math1 (Atoh1))
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
Although the optimal Ig concentration for an application varies for each product and must be optimized for each laboratory, a good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) is 2-5 ug/ml. For western blots, the recommended concentration range is 0.2-0.5 ug/ml.
All cell products contain the antimicrobial ProClin. Click here for additional information.

12 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • FFPE References
  • All References
  • Initial Publication

    Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice.
    Kawakami T
    The Angle orthodontist 75.6 (2005 Nov): 993-5.

    IF References
    WB References
    IHC References
    FFPE References
    All References

    Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice.
    Kawakami T
    The Angle orthodontist 75.6 (2005 Nov): 993-5.

    Lateral line placodes of aquatic vertebrates are evolutionarily conserved in mammals.
    Knabe W
    Biology open 7.6 (2018 Jun 19): .

    The roof plate regulates cerebellar cell-type specification and proliferation.
    Millen KJ
    Development (Cambridge, England) 133.15 (2006 Aug): 2793-804.

    Generation of cerebellar neuron precursors from embryonic stem cells.
    Sasai Y
    Developmental biology 290.2 (2006 Feb 15): 287-96.

    Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation.
    Huang Z
    The Journal of neuroscience : the official journal of the Society for Neuroscience 32.43 (2012 Oct 24): 14979-93.

    Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells.
    Hu Z
    Frontiers in cellular neuroscience 10. (2016): 185.

    Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord.
    Robert B
    Development (Cambridge, England) 141.8 (2014 Apr): 1726-36.

    Environmental cues from CNS, PNS, and ENS cells regulate CNS progenitor differentiation.
    Fex Svenningsen A
    Neuroreport 19.13 (2008 Aug 27): 1283-9.

    Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum.
    Ogawa M
    Neural development 5. (2010 Sep 1): 23.

    Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
    Ayrault O
    Developmental cell 48.2 (2019 Jan 28): 184-199.e5.

    Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.
    Roussel MF
    Molecular cancer research : MCR 7.1 (2009 Jan): 33-40.

    The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
    McMahon AP
    Genes & development 21.10 (2007 May 15): 1244-57.

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