Tango

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$40.00
SKU: Tango
View product citations for antibody Tango on CiteAb

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DSHB Data Sheet

Catalog Fields

Antigen: Tango
Hybridoma Cells Available: Yes
Antigen Species: Drosophila melanogaster
Depositor: Crews, S.
Isotype: MIgG2a
Antigen Sequence:
Host Species: mouse
Depositors Institution: University of North Carolina at Chapel Hill
Positive Tested Species Reactivity: Drosophila
Depositors Notes: Strong reduction in staining in mutant embryos.
Antigen Molecular Weight: Predicted: 71 kDa
Human Protein Atlas:  
Predicted Species Reactivity:  
Gene: tgo
Immunogen: Recombinant Tgo (aa 1-393)/Gst fusion protein.
Alternate Gene Names: CG11987, dARNT, tango, bHLHe4, HIF-1beta
Alternate Antibody Name: mAb-Tgo
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped: Yes
Myeloma Strain: P3x63 Ag8 653
Epitope Location or Sequence: aa 1-393
Uniprot ID: O15945 
Immunogen Sequence: Partial protein
Entrez Gene ID: 41084 
Additional Characterization:  
Antibody Registry ID: AB_528486 
Additional Information:
Recommended Applications: Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
Tango was deposited to the DSHB by Crews, S. (DSHB Hybridoma Product Tango)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. For immediate use, short term storage at 4°C up to two weeks is recommended. For long term storage, divide the solution into volumes of no less than 20 ul for freezing at -20°C or -80°C. The small volume aliquot should provide sufficient reagent for short term use. Freeze-thaw cycles should be avoided. For concentrate or bioreactor products, an equal volume of glycerol, a cryoprotectant, may be added prior to freezing.
Usage Recommendations
Although the optimal Ig concentration for an application varies for each product and must be optimized for each laboratory, a good starting concentration for immunohistochemistry (IHC), immunofluorescence (IF), and immunocytochemistry (ICC) is 2-5 ug/ml. For western blots, the recommended concentration range is 0.2-0.5 ug/ml.
All cell products contain the antimicrobial ProClin. Click here for additional information.

13 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • IP References
  • Epitope Map References
  • All References
  • Initial Publication
    IF References

    Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis.
    Crews ST
    Development (Cambridge, England) 125.9 (1998 May): 1599-608.

    Common origin of insect trachea and endocrine organs from a segmentally repeated precursor.
    Castelli-Gair Hombría J
    Current biology : CB 24.1 (2014 Jan 6): 76-81.

    The bHLH-PAS transcription factor dysfusion regulates tarsal joint formation in response to Notch activity during drosophila leg development.
    Estella C
    PLoS genetics 10.10 (2014 Oct): e1004621.

    Rac1 controls epithelial tube length through the apical secretion and polarity pathways.
    Laprise P
    Biology open 5.1 (2015 Dec 23): 49-54.

    Precise long-range migration results from short-range stepwise migration during ring gland organogenesis.
    Hombría JC
    Developmental biology 414.1 (2016 Jun 1): 45-57.

    The Drosophila jing gene is a downstream target in the Trachealess/Tango tracheal pathway.
    Sonnenfeld M
    Development genes and evolution 220.7-8 (2010 Dec): 191-206.

    The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons.
    Jan YN
    Genes & development 20.20 (2006 Oct 15): 2806-19.

    Drosophila Jing is part of the breathless fibroblast growth factor receptor positive feedback loop.
    Sun X
    Development genes and evolution 220.7-8 (2010 Dec): 207-20.

    Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia.
    Moberg KH
    Developmental biology 329.2 (2009 May 15): 294-305.

    Epithelial polarity proteins regulate Drosophila tracheal tube size in parallel to the luminal matrix pathway.
    Tepass U
    Current biology : CB 20.1 (2010 Jan 12): 55-61.

    WB References
    IHC References
    IP References
    Epitope Map References
    All References

    The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development.
    Crews S
    Development (Cambridge, England) 124.22 (1997 Nov): 4571-82.

    Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia.
    Moberg KH
    Developmental biology 329.2 (2009 May 15): 294-305.

    Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis.
    Crews ST
    Development (Cambridge, England) 125.9 (1998 May): 1599-608.

    Common origin of insect trachea and endocrine organs from a segmentally repeated precursor.
    Castelli-Gair Hombría J
    Current biology : CB 24.1 (2014 Jan 6): 76-81.

    The bHLH-PAS transcription factor dysfusion regulates tarsal joint formation in response to Notch activity during drosophila leg development.
    Estella C
    PLoS genetics 10.10 (2014 Oct): e1004621.

    Rac1 controls epithelial tube length through the apical secretion and polarity pathways.
    Laprise P
    Biology open 5.1 (2015 Dec 23): 49-54.

    Precise long-range migration results from short-range stepwise migration during ring gland organogenesis.
    Hombría JC
    Developmental biology 414.1 (2016 Jun 1): 45-57.

    The Drosophila jing gene is a downstream target in the Trachealess/Tango tracheal pathway.
    Sonnenfeld M
    Development genes and evolution 220.7-8 (2010 Dec): 191-206.

    The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons.
    Jan YN
    Genes & development 20.20 (2006 Oct 15): 2806-19.

    Drosophila Jing is part of the breathless fibroblast growth factor receptor positive feedback loop.
    Sun X
    Development genes and evolution 220.7-8 (2010 Dec): 207-20.

    Epithelial polarity proteins regulate Drosophila tracheal tube size in parallel to the luminal matrix pathway.
    Tepass U
    Current biology : CB 20.1 (2010 Jan 12): 55-61.

    A conserved role for Drosophila Neuroglian and human L1-CAM in central-synapse formation.
    Murphey RK
    Current biology : CB 16.1 (2006 Jan 10): 12-23.

    Regulation of the Drosophila hypoxia-inducible factor alpha Sima by CRM1-dependent nuclear export.
    Wappner P
    Molecular and cellular biology 28.10 (2008 May): 3410-23.

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