TROMA-III

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$40.00
SKU: TROMA-III
View product citations for antibody TROMA-III on CiteAb

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DSHB Data Sheet

Catalog Fields

Antigen: Keratin, type I; cytokeratin 19
Hybridoma Cells Available: Yes
Antigen Species: Mouse
Depositor: Kemler, R.
Isotype: RIgG2a, kappa light chain
Antigen Sequence:
Host Species: rat
Depositors Institution: MPI fuer Immunobiologie
Positive Tested Species Reactivity: Human, Mouse
Depositors Notes: Methanol: acetone (1:1) fixation works well for cultured cells.
Antigen Molecular Weight: Predicted: 44.5 kDa
Human Protein Atlas:
Predicted Species Reactivity:  
Gene: Krt19
Immunogen: TDM1 (Trophoblastoma) cell line intermediate filaments
Alternate Gene Names: Krt1-19
Alternate Antibody Name:
Clonality: Monoclonal
Alternate Antigen Name:
Epitope Mapped:
Myeloma Strain: SP2/0
Epitope Location or Sequence:
Uniprot ID: P19001 
Immunogen Sequence: Full length protein
Entrez Gene ID: 16669 
Additional Characterization:
Antibody Registry ID: AB_2133570 
Additional Information:
Recommended Applications: FACS, FFPE, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
These hybridomas were created by your colleagues. Please acknowledge the hybridoma contributor and the Developmental Studies Hybridoma Bank (DSHB) in the Materials and Methods of your publications. Please email the citation to us.
For your Materials & Methods section:
TROMA-III was deposited to the DSHB by Kemler, R. (DSHB Hybridoma Product TROMA-III)
Storage and Handling Recommendations
Although many cell products are maintained at 4°C for years without loss of activity, shelf-life at 4°C is highly variable. To ensure retention of antibody activity, we recommend aliquotting the product into two parts: 1) a volume of antibody stored at 4°C to be used within two weeks. 2) the remaining product diluted with an equal volume of molecular grade glycerol and stored at -20°C.
Usage Recommendations
While optimal Ig concentration for an application will vary, a good starting concentration for immunohistochemistry (IHC), immunofluorescence(IF) and staining is 2-5 µg/ml. For Western blots, the concentration is decreased by one order of magnitude (that is, 0.2-0.5 µg/ml).
All cell products contain the antimicrobial ProClin. Click here for additional information.

163 References

  • Initial Publication
  • IF References
  • WB References
  • IHC References
  • FFPE References
  • FACS References
  • All References
  • Initial Publication

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    IF References

    Arid1a restrains Kras-dependent changes in acinar cell identity.
    Lowe SW
    eLife 7. (2018 Jul 17): .

    Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis.
    Fuster G
    Breast cancer research : BCR 20.1 (2018 Jul 4): 65.

    HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.
    Schwabe RF
    The Journal of clinical investigation 128.6 (2018 Jun 1): 2436-2451.

    Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.
    McNamara NA
    PloS one 12.9 (2017): e0184916.

    The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals.
    Bai H
    Laboratory investigation; a journal of technical methods and pathology 97.7 (2017 Jul): 843-853.

    Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.
    Crawford HC
    Cellular and molecular gastroenterology and hepatology 3.1 (2017 Jan): 99-118.

    Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
    Österreicher CH
    Oncotarget 7.52 (2016 Dec 27): 86985-86998.

    Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma.
    Gao ZH
    Oncotarget 7.47 (2016 Nov 22): 77838-77853.

    SOX2 regulates acinar cell development in the salivary gland.
    Knox SM
    eLife 6. (2017 Jun 17): .

    Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration.
    Zhou B
    The Journal of biological chemistry 292.21 (2017 May 26): 8594-8604.

    Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
    Kobayashi A
    Developmental cell 41.4 (2017 May 22): 349-365.e3.

    Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models.
    Dezső K
    PloS one 12.4 (2017): e0176518.

    Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.
    Charles RP
    Oncotarget 8.15 (2017 Apr 11): 24604-24620.

    FGF21 Is an Exocrine Pancreas Secretagogue.
    Mangelsdorf DJ
    Cell metabolism 25.2 (2017 Feb 7): 472-480.

    Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration.
    Zhou B
    Nature communications 7. (2016 Nov 18): 13369.

    LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
    Bardeesy N
    Nature 539.7629 (2016 Nov 17): 390-395.

    Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice.
    van Grunsven LA
    Scientific reports 6. (2016 Nov 8): 36586.

    Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.
    van Grunsven LA
    PloS one 11.9 (2016): e0162286.

    Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
    Ostrowski MC
    Neoplasia (New York, N.Y.) 18.9 (2016 Sep): 541-52.

    The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.
    Wells RG
    Hepatology (Baltimore, Md.) 64.3 (2016 Sep): 880-93.

    Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.
    Miyazaki J
    PloS one 11.8 (2016): e0161190.

    K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds.
    Stepp MA
    Developmental dynamics : an official publication of the American Association of Anatomists 245.2 (2016 Feb): 132-43.

    Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
    Pikarsky E
    Nature immunology 16.12 (2015 Dec): 1235-44.

    Comparison of methods for the isolation of human breast epithelial and myoepithelial cells.
    Gascón P
    Frontiers in cell and developmental biology 3. (2015): 32.

    Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice.
    Esni F
    Gastroenterology 147.5 (2014 Nov): 1106-18.e11.

    The biliary epithelium gives rise to liver progenitor cells.
    Sancho-Bru P
    Hepatology (Baltimore, Md.) 60.4 (2014 Oct): 1367-77.

    Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.
    Fuchs P
    PloS one 9.9 (2014): e108323.

    Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
    Knox SM
    Developmental cell 30.4 (2014 Aug 25): 449-62.

    Tannic acid label indicates abnormal cell development coinciding with regeneration of renal tubules.
    Denk L
    BMC clinical pathology 14. (2014): 34.

    Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors.
    LaBarge MA
    Cell reports 7.6 (2014 Jun 26): 1926-39.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
    Machesky LM
    Gastroenterology 146.5 (2014 May): 1386-96.e1-17.

    MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
    Pasca di Magliano M
    Gastroenterology 146.3 (2014 Mar): 822-834.e7.

    Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Means AL
    Oncogene 33.7 (2014 Feb 13): 823-31.

    Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver.
    Loomes KM
    PloS one 8.12 (2013): e84383.

    Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
    Korc M
    The Journal of clinical investigation 124.1 (2014 Jan): 338-52.

    Keratin 8 modulates β-cell stress responses and normoglycaemia.
    Toivola DM
    Journal of cell science 126.Pt 24 (2013 Dec 15): 5635-44.

    A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration.
    Tsai RY
    Hepatology (Baltimore, Md.) 58.6 (2013 Dec): 2176-87.

    Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy.
    Batra SK
    PloS one 8.11 (2013): e80580.

    Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
    Schwabe RF
    Nature communications 4. (2013): 2823.

    Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
    Philips MR
    The Journal of clinical investigation 123.11 (2013 Nov): 4681-94.

    Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
    di Magliano MP
    Cancer research 73.20 (2013 Oct 15): 6359-74.

    Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length.
    LaBarge MA
    Genome integrity 4.1 (2013 May 29): 4.

    Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.
    Guiot Y
    American journal of physiology. Endocrinology and metabolism 304.7 (2013 Apr 1): E711-23.

    Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells.
    Niemann H
    Stem cells and development 22.1 (2013 Jan 1): 124-35.

    Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine.
    Leiter AB
    Developmental biology 371.2 (2012 Nov 15): 156-69.

    Rotavirus infection of human cholangiocytes parallels the murine model of biliary atresia.
    Tiao G
    The Journal of surgical research 177.2 (2012 Oct): 275-81.

    c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 302.12 (2012 Jun 15): G1381-96.

    Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia.
    Bar-Sagi D
    Cancer cell 21.6 (2012 Jun 12): 836-47.

    Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.
    Murray NR
    PloS one 7.2 (2012): e30509.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
    Omary MB
    The Journal of cell biology 195.2 (2011 Oct 17): 217-29.

    Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.
    Esni F
    Gastroenterology 141.4 (2011 Oct): 1451-62, 1462.e1-6.

    Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis.
    Wells RG
    Hepatology (Baltimore, Md.) 53.5 (2011 May): 1685-95.

    Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
    Diehl AM
    American journal of physiology. Gastrointestinal and liver physiology 300.2 (2011 Feb): G303-15.

    Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.
    Omary MB
    Proceedings of the National Academy of Sciences of the United States of America 108.4 (2011 Jan 25): 1445-50.

    Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
    Iruela-Arispe ML
    Development (Cambridge, England) 137.23 (2010 Dec): 4061-72.

    Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation.
    Benedetti A
    Journal of hepatology 53.4 (2010 Oct): 663-70.

    Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice.
    Kisseleva T
    Gastroenterology 139.3 (2010 Sep): 987-98.

    Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.
    Omary MB
    Gastroenterology 138.4 (2010 Apr): 1607-17.

    Cytokeratin expression during mouse embryonic and early postnatal mammary gland development.
    Dai X
    Histochemistry and cell biology 133.2 (2010 Feb): 213-21.

    DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
    Pezzano M
    PloS one 5.2 (2010 Feb 8): e9062.

    Cytokeratin expression during mouse embryonic and early postnatal mammary gland development.
    Dai X
    Histochemistry and cell biology 133.2 (2010 Feb): 213-21.

    Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
    Leclercq IA
    Hepatology (Baltimore, Md.) 49.5 (2009 May): 1625-35.

    Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.
    Navarro P
    Gastroenterology 136.4 (2009 Apr): 1379-90, e1-5.

    Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments.
    Bissell MJ
    Integrative biology : quantitative biosciences from nano to macro 1.1 (2009 Jan): 70-9.

    Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction.
    Dhouailly D
    Developmental dynamics : an official publication of the American Association of Anatomists 236.3 (2007 Mar): 755-68.

    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
    Omary MB
    Journal of cell science 117.Pt 9 (2004 Apr 1): 1709-19.

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
    Dupont S
    Journal of hepatology 71.1 (2019 Jul): 130-142.

    Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.
    Labarge MA
    Cancer research 72.14 (2012 Jul 15): 3687-701.

    High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia.
    Lorens JB
    Cell reports 23.4 (2018 Apr 24): 1205-1219.

    Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
    Dong XC
    Biochimica et biophysica acta. Molecular basis of disease 1865.10 (2019 Oct 1): 2685-2693.

    Chondrocyte-like nested cells in the aged intervertebral disc are late-stage nucleus pulposus cells.
    Dahia CL
    Aging cell 18.5 (2019 Oct): e13006.

    WB References

    Generation and characterisation of keratin 7 (K7) knockout mice.
    McLean WH
    PloS one 8.5 (2013): e64404.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
    Omary MB
    The Journal of cell biology 195.2 (2011 Oct 17): 217-29.

    Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
    Diehl AM
    American journal of physiology. Gastrointestinal and liver physiology 300.2 (2011 Feb): G303-15.

    Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
    Omary MB
    The Journal of biological chemistry 286.3 (2011 Jan 21): 2273-84.

    Tumor-initiating function of nucleostemin-enriched mammary tumor cells.
    Tsai RY
    Cancer research 70.22 (2010 Nov 15): 9444-52.

    Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.
    Omary MB
    Gastroenterology 138.4 (2010 Apr): 1607-17.

    Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity.
    Omary MB
    Hepatology (Baltimore, Md.) 50.2 (2009 Aug): 546-54.

    Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
    Trauner M
    Hepatology (Baltimore, Md.) 49.6 (2009 Jun): 1972-81.

    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
    Omary MB
    Journal of cell science 117.Pt 9 (2004 Apr 1): 1709-19.

    Keratins modulate colonocyte electrolyte transport via protein mistargeting.
    Omary MB
    The Journal of cell biology 164.6 (2004 Mar 15): 911-21.

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    IHC References

    CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
    Zhao X
    Oncogene 37.1 (2018 Jan 4): 128-138.

    Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis.
    Valverde ÁM
    Molecular metabolism 7. (2018 Jan): 132-146.

    The Cholangiocyte Adenosine-IL-6 Axis Regulates Survival During Biliary Cirrhosis.
    Dranoff JA
    Gene expression 17.4 (2017 Nov 27): 327-340.

    Notch signaling and progenitor/ductular reaction in steatohepatitis.
    Strazzabosco M
    PloS one 12.11 (2017): e0187384.

    Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
    Behrens A
    Cell reports 21.4 (2017 Oct 24): 966-978.

    Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
    Strömblad S
    Scientific reports 7.1 (2017 Aug 1): 7031.

    Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
    Pasparakis M
    The Journal of clinical investigation 127.7 (2017 Jun 30): 2662-2677.

    NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
    Miller G
    The Journal of experimental medicine 214.6 (2017 Jun 5): 1711-1724.

    Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree.
    Tanaka M
    PloS one 12.4 (2017): e0175355.

    Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes.
    Marzioni M
    The American journal of pathology 187.2 (2017 Feb): 366-376.

    Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.
    Crawford HC
    Cellular and molecular gastroenterology and hepatology 3.1 (2017 Jan): 99-118.

    Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice.
    van Grunsven LA
    Scientific reports 6. (2016 Nov 8): 36586.

    Keratins Are Altered in Intestinal Disease-Related Stress Responses.
    Toivola DM
    Cells 5.3 (2016 Sep 10): .

    Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
    Ostrowski MC
    Neoplasia (New York, N.Y.) 18.9 (2016 Sep): 541-52.

    Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
    Christen U
    Cell adhesion and migration 10.4 (2016 Jul 3): 419-33.

    Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.
    Tirnitz-Parker JEE
    The American journal of pathology 186.7 (2016 Jul): 1762-1774.

    LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
    Lim DS
    Nature communications 7. (2016 Jun 30): 11961.

    Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet.
    Brigstock DR
    Gene expression 17.1 (2016): 47-59.

    Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice.
    Miller G
    Gastroenterology 150.7 (2016 Jun): 1659-1672.e5.

    Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
    Sage J
    Genes and development 30.7 (2016 Apr 1): 772-85.

    Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.
    Strazzabosco M
    Hepatology (Baltimore, Md.) 62.6 (2015 Dec): 1828-39.

    YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.
    Tchorz JS
    Hepatology (Baltimore, Md.) 62.5 (2015 Nov): 1497-510.

    Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
    Siveke JT
    Nature medicine 21.10 (2015 Oct): 1163-71.

    Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.
    Chiba T
    Cancer research 75.16 (2015 Aug 15): 3292-301.

    Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
    Winslow MM
    Genes and development 29.14 (2015 Jul 15): 1576-85.

    Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
    Lamers WH
    Developmental biology 396.2 (2014 Dec 15): 201-13.

    PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
    Crawford HC
    Gastroenterology 147.6 (2014 Dec): 1405-16.e7.

    Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.
    Pasparakis M
    Cell death and differentiation 21.11 (2014 Nov): 1721-32.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression.
    Fernandez-Zapico ME
    The Journal of biological chemistry 289.23 (2014 Jun 6): 16516-25.

    Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
    David G
    The Journal of clinical investigation 124.5 (2014 May): 2125-35.

    CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.
    di Magliano MP
    Cancer immunology research 2.5 (2014 May): 423-35.

    Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
    Savatier P
    Nature communications 5. (2014 Apr 28): 3719.

    Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant.
    Stephen LA
    Organogenesis 10.2 (2014 Apr-Jun): 177-85.

    Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 306.8 (2014 Apr 15): G670-6.

    All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
    Boyer JL
    The Journal of pharmacology and experimental therapeutics 349.1 (2014 Apr): 94-8.

    Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.
    Forbes SJ
    Hepatology (Baltimore, Md.) 60.5 (2014 Nov): 1727-40.

    Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Means AL
    Oncogene 33.7 (2014 Feb 13): 823-31.

    Cholestasis induces reversible accumulation of periplakin in mouse liver.
    Gonzalez FJ
    BMC gastroenterology 13. (2013 Jul 13): 116.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
    Rustgi AK
    Genes and development 27.3 (2013 Feb 1): 288-300.

    FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.
    Miyajima A
    Genes and development 27.2 (2013 Jan 15): 169-81.

    Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
    di Magliano MP
    PloS one 7.12 (2012): e49707.

    Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.
    Leclercq IA
    Gastroenterology 143.6 (2012 Dec): 1564-1575.e7.

    A porcine model of familial adenomatous polyposis.
    Schnieke A
    Gastroenterology 143.5 (2012 Nov): 1173-1175.e7.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
    PloS one 6.11 (2011): e27725.

    Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
    Miyazaki J
    PloS one 7.10 (2012): e47536.

    GATA4 and GATA6 control mouse pancreas organogenesis.
    Rojas A
    The Journal of clinical investigation 122.10 (2012 Oct): 3504-15.

    EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
    Siveke JT
    Cancer cell 22.3 (2012 Sep 11): 304-17.

    Yes-associated protein regulates the hepatic response after bile duct ligation.
    Anders RA
    Hepatology (Baltimore, Md.) 56.3 (2012 Sep): 1097-107.

    MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.
    Siveke JT
    PloS one 7.6 (2012): e39424.

    Development and characterization of an organotypic model of Barrett's esophagus.
    Maley CC
    Journal of cellular physiology 227.6 (2012 Jun): 2654-9.

    A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
    Korc M
    Oncogene 31.20 (2012 May 17): 2535-44.

    Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 302.9 (2012 May 1): G925-36.

    Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.
    Pasca di Magliano M
    The Journal of clinical investigation 122.2 (2012 Feb): 639-53.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
    PloS one 6.11 (2011): e27725.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury.
    Leclercq I
    The American journal of pathology 179.4 (2011 Oct): 1839-50.

    Osteopontin upregulation in rotavirus-induced murine biliary atresia requires replicating virus but is not necessary for development of biliary atresia.
    Estes MK
    Virology 417.2 (2011 Sep 1): 281-92.

    Early requirement of Rac1 in a mouse model of pancreatic cancer.
    Siveke JT
    Gastroenterology 141.2 (2011 Aug): 719-30, 730.e1-7.

    PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
    DePinho RA
    Cancer discovery 1.2 (2011 Jul): 158-69.

    Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.
    Barbacid M
    Cancer cell 19.6 (2011 Jun 14): 728-39.

    Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice.
    Huppert SS
    Disease models and mechanisms 4.3 (2011 May): 359-67.

    Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.
    Omary MB
    Proceedings of the National Academy of Sciences of the United States of America 108.4 (2011 Jan 25): 1445-50.

    Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
    Bar-Sagi D
    Cancer cell 18.5 (2010 Nov 16): 448-58.

    Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis.
    Boyer JL
    Hepatology (Baltimore, Md.) 51.1 (2010 Jan): 181-90.

    Foxl1 promotes liver repair following cholestatic injury in mice.
    Greenbaum LE
    Laboratory investigation; a journal of technical methods and pathology 89.12 (2009 Dec): 1387-96.

    Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms.
    Copple BL
    Liver international : official journal of the International Association for the Study of the Liver 30.5 (2010 May): 669-82.

    Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis.
    Boyer JL
    Hepatology (Baltimore, Md.) 51.1 (2010 Jan): 181-90.

    Foxl1 promotes liver repair following cholestatic injury in mice.
    Greenbaum LE
    Laboratory investigation; a journal of technical methods and pathology 89.12 (2009 Dec): 1387-96.

    Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
    Reisinger EC
    Tropical medicine and international health : TM and IH 14.11 (2009 Nov): 1418-25.

    E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
    Saur D
    Gastroenterology 137.1 (2009 Jul): 361-71, 371.e1-5.

    High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model.
    Gorden DL
    The American journal of pathology 175.1 (2009 Jul): 355-64.

    Foxa1 and Foxa2 regulate bile duct development in mice.
    Kaestner KH
    The Journal of clinical investigation 119.6 (2009 Jun): 1537-45.

    Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
    Trauner M
    Hepatology (Baltimore, Md.) 49.6 (2009 Jun): 1972-81.

    Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.
    Korc M
    Biochemical and biophysical research communications 382.3 (2009 May 8): 561-5.

    Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
    Leclercq IA
    Hepatology (Baltimore, Md.) 49.5 (2009 May): 1625-35.

    Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
    de Sauvage FJ
    Proceedings of the National Academy of Sciences of the United States of America 106.11 (2009 Mar 17): 4254-9.

    Cytoskeletal proteins in thymic epithelial cells of the Australian lungfish Neoceratodus forsteri.
    Joss J
    Journal of anatomy 214.1 (2009 Jan): 140-52.

    Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.
    Rustgi AK
    PloS one 3.10 (2008): e3534.

    Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice.
    Greenberg HB
    Journal of virology 82.15 (2008 Aug): 7578-90.

    Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.
    Matzuk MM
    Molecular and cellular biology 28.1 (2008 Jan): 248-57.

    Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.
    Omary MB
    Molecular biology of the cell 18.12 (2007 Dec): 4969-78.

    Intraovarian activins are required for female fertility.
    Matzuk MM
    Molecular endocrinology (Baltimore, Md.) 21.10 (2007 Oct): 2458-71.

    Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.
    Cho KR
    Cancer cell 11.4 (2007 Apr): 321-33.

    Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.
    Cho KR
    Cancer cell 11.4 (2007 Apr): 321-33.

    The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia.
    Korc M
    Proceedings of the National Academy of Sciences of the United States of America 104.11 (2007 Mar 13): 4437-42.

    Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
    Hebrok M
    Genes and development 20.22 (2006 Nov 15): 3161-73.

    In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas.
    Chen Y
    Proceedings of the National Academy of Sciences of the United States of America 103.6 (2006 Feb 7): 1858-63.

    Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
    Trauner M
    The American journal of pathology 168.2 (2006 Feb): 410-22.

    24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
    Trauner M
    Gastroenterology 130.2 (2006 Feb): 465-81.

    Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development.
    Jacob F
    Journal of embryology and experimental morphology 64. (1981 Aug): 45-60.

    Genetic Lineage Tracing of Biliary Epithelial Cells.
    Sancho-Bru P
    Methods in molecular biology (Clifton, N.J.) 1905. (2019): 45-57.

    TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma.
    Ikehara Y
    Scientific reports 9.1 (2019 Aug 2): 11247.

    Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
    Dong XC
    Biochimica et biophysica acta. Molecular basis of disease 1865.10 (2019 Oct 1): 2685-2693.

    FFPE References

    Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
    Strömblad S
    Scientific reports 7.1 (2017 Aug 1): 7031.

    The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals.
    Bai H
    Laboratory investigation; a journal of technical methods and pathology 97.7 (2017 Jul): 843-853.

    Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
    Pasparakis M
    The Journal of clinical investigation 127.7 (2017 Jun 30): 2662-2677.

    NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
    Miller G
    The Journal of experimental medicine 214.6 (2017 Jun 5): 1711-1724.

    Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
    Ostrowski MC
    Genes and development 30.17 (2016 Sep 1): 1943-55.

    Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.
    Tirnitz-Parker JEE
    The American journal of pathology 186.7 (2016 Jul): 1762-1774.

    LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
    Lim DS
    Nature communications 7. (2016 Jun 30): 11961.

    Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet.
    Brigstock DR
    Gene expression 17.1 (2016): 47-59.

    Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice.
    Miller G
    Gastroenterology 150.7 (2016 Jun): 1659-1672.e5.

    Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
    Sage J
    Genes and development 30.7 (2016 Apr 1): 772-85.

    Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
    Pikarsky E
    Nature immunology 16.12 (2015 Dec): 1235-44.

    Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.
    Strazzabosco M
    Hepatology (Baltimore, Md.) 62.6 (2015 Dec): 1828-39.

    Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
    Siveke JT
    Nature medicine 21.10 (2015 Oct): 1163-71.

    Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.
    Chiba T
    Cancer research 75.16 (2015 Aug 15): 3292-301.

    Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
    Winslow MM
    Genes and development 29.14 (2015 Jul 15): 1576-85.

    Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
    Lamers WH
    Developmental biology 396.2 (2014 Dec 15): 201-13.

    PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
    Crawford HC
    Gastroenterology 147.6 (2014 Dec): 1405-16.e7.

    Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.
    Pasparakis M
    Cell death and differentiation 21.11 (2014 Nov): 1721-32.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression.
    Fernandez-Zapico ME
    The Journal of biological chemistry 289.23 (2014 Jun 6): 16516-25.

    Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
    David G
    The Journal of clinical investigation 124.5 (2014 May): 2125-35.

    Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
    Savatier P
    Nature communications 5. (2014 Apr 28): 3719.

    Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant.
    Stephen LA
    Organogenesis 10.2 (2014 Apr-Jun): 177-85.

    Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 306.8 (2014 Apr 15): G670-6.

    All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
    Boyer JL
    The Journal of pharmacology and experimental therapeutics 349.1 (2014 Apr): 94-8.

    Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.
    Forbes SJ
    Hepatology (Baltimore, Md.) 60.5 (2014 Nov): 1727-40.

    Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
    Korc M
    The Journal of clinical investigation 124.1 (2014 Jan): 338-52.

    A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration.
    Tsai RY
    Hepatology (Baltimore, Md.) 58.6 (2013 Dec): 2176-87.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
    Rustgi AK
    Genes and development 27.3 (2013 Feb 1): 288-300.

    A porcine model of familial adenomatous polyposis.
    Schnieke A
    Gastroenterology 143.5 (2012 Nov): 1173-1175.e7.

    Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
    Miyazaki J
    PloS one 7.10 (2012): e47536.

    GATA4 and GATA6 control mouse pancreas organogenesis.
    Rojas A
    The Journal of clinical investigation 122.10 (2012 Oct): 3504-15.

    EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
    Siveke JT
    Cancer cell 22.3 (2012 Sep 11): 304-17.

    Yes-associated protein regulates the hepatic response after bile duct ligation.
    Anders RA
    Hepatology (Baltimore, Md.) 56.3 (2012 Sep): 1097-107.

    MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.
    Siveke JT
    PloS one 7.6 (2012): e39424.

    Development and characterization of an organotypic model of Barrett's esophagus.
    Maley CC
    Journal of cellular physiology 227.6 (2012 Jun): 2654-9.

    A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
    Korc M
    Oncogene 31.20 (2012 May 17): 2535-44.

    Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 302.9 (2012 May 1): G925-36.

    Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.
    Pasca di Magliano M
    The Journal of clinical investigation 122.2 (2012 Feb): 639-53.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
    PloS one 6.11 (2011): e27725.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
    PloS one 6.11 (2011): e27725.

    Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.
    Omary MB
    Proceedings of the National Academy of Sciences of the United States of America 108.4 (2011 Jan 25): 1445-50.

    Foxl1 promotes liver repair following cholestatic injury in mice.
    Greenbaum LE
    Laboratory investigation; a journal of technical methods and pathology 89.12 (2009 Dec): 1387-96.

    Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis.
    Boyer JL
    Hepatology (Baltimore, Md.) 51.1 (2010 Jan): 181-90.

    Foxl1 promotes liver repair following cholestatic injury in mice.
    Greenbaum LE
    Laboratory investigation; a journal of technical methods and pathology 89.12 (2009 Dec): 1387-96.

    E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
    Saur D
    Gastroenterology 137.1 (2009 Jul): 361-71, 371.e1-5.

    High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model.
    Gorden DL
    The American journal of pathology 175.1 (2009 Jul): 355-64.

    Foxa1 and Foxa2 regulate bile duct development in mice.
    Kaestner KH
    The Journal of clinical investigation 119.6 (2009 Jun): 1537-45.

    Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.
    Korc M
    Biochemical and biophysical research communications 382.3 (2009 May 8): 561-5.

    Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
    Leclercq IA
    Hepatology (Baltimore, Md.) 49.5 (2009 May): 1625-35.

    Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
    de Sauvage FJ
    Proceedings of the National Academy of Sciences of the United States of America 106.11 (2009 Mar 17): 4254-9.

    Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.
    Rustgi AK
    PloS one 3.10 (2008): e3534.

    Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.
    Matzuk MM
    Molecular and cellular biology 28.1 (2008 Jan): 248-57.

    Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.
    Omary MB
    Molecular biology of the cell 18.12 (2007 Dec): 4969-78.

    Intraovarian activins are required for female fertility.
    Matzuk MM
    Molecular endocrinology (Baltimore, Md.) 21.10 (2007 Oct): 2458-71.

    Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.
    Cho KR
    Cancer cell 11.4 (2007 Apr): 321-33.

    Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
    Dong XC
    Biochimica et biophysica acta. Molecular basis of disease 1865.10 (2019 Oct 1): 2685-2693.

    TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma.
    Ikehara Y
    Scientific reports 9.1 (2019 Aug 2): 11247.

    FACS References
    All References

    CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
    Zhao X
    Oncogene 37.1 (2018 Jan 4): 128-138.

    Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis.
    Valverde ÁM
    Molecular metabolism 7. (2018 Jan): 132-146.

    The Cholangiocyte Adenosine-IL-6 Axis Regulates Survival During Biliary Cirrhosis.
    Dranoff JA
    Gene expression 17.4 (2017 Nov 27): 327-340.

    Notch signaling and progenitor/ductular reaction in steatohepatitis.
    Strazzabosco M
    PloS one 12.11 (2017): e0187384.

    Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
    Behrens A
    Cell reports 21.4 (2017 Oct 24): 966-978.

    Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
    Strömblad S
    Scientific reports 7.1 (2017 Aug 1): 7031.

    Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
    Pasparakis M
    The Journal of clinical investigation 127.7 (2017 Jun 30): 2662-2677.

    NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
    Miller G
    The Journal of experimental medicine 214.6 (2017 Jun 5): 1711-1724.

    Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree.
    Tanaka M
    PloS one 12.4 (2017): e0175355.

    Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes.
    Marzioni M
    The American journal of pathology 187.2 (2017 Feb): 366-376.

    Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.
    Crawford HC
    Cellular and molecular gastroenterology and hepatology 3.1 (2017 Jan): 99-118.

    Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice.
    van Grunsven LA
    Scientific reports 6. (2016 Nov 8): 36586.

    Keratins Are Altered in Intestinal Disease-Related Stress Responses.
    Toivola DM
    Cells 5.3 (2016 Sep 10): .

    Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
    Ostrowski MC
    Neoplasia (New York, N.Y.) 18.9 (2016 Sep): 541-52.

    Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
    Christen U
    Cell adhesion and migration 10.4 (2016 Jul 3): 419-33.

    Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.
    Tirnitz-Parker JEE
    The American journal of pathology 186.7 (2016 Jul): 1762-1774.

    LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
    Lim DS
    Nature communications 7. (2016 Jun 30): 11961.

    Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet.
    Brigstock DR
    Gene expression 17.1 (2016): 47-59.

    Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice.
    Miller G
    Gastroenterology 150.7 (2016 Jun): 1659-1672.e5.

    Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
    Sage J
    Genes and development 30.7 (2016 Apr 1): 772-85.

    Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.
    Strazzabosco M
    Hepatology (Baltimore, Md.) 62.6 (2015 Dec): 1828-39.

    YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.
    Tchorz JS
    Hepatology (Baltimore, Md.) 62.5 (2015 Nov): 1497-510.

    Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
    Siveke JT
    Nature medicine 21.10 (2015 Oct): 1163-71.

    Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.
    Chiba T
    Cancer research 75.16 (2015 Aug 15): 3292-301.

    Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
    Winslow MM
    Genes and development 29.14 (2015 Jul 15): 1576-85.

    Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
    Lamers WH
    Developmental biology 396.2 (2014 Dec 15): 201-13.

    PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
    Crawford HC
    Gastroenterology 147.6 (2014 Dec): 1405-16.e7.

    Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.
    Pasparakis M
    Cell death and differentiation 21.11 (2014 Nov): 1721-32.

    Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
    Tournier C
    Cancer research 74.12 (2014 Jun 15): 3344-56.

    Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression.
    Fernandez-Zapico ME
    The Journal of biological chemistry 289.23 (2014 Jun 6): 16516-25.

    Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
    David G
    The Journal of clinical investigation 124.5 (2014 May): 2125-35.

    CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.
    di Magliano MP
    Cancer immunology research 2.5 (2014 May): 423-35.

    Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
    Savatier P
    Nature communications 5. (2014 Apr 28): 3719.

    Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant.
    Stephen LA
    Organogenesis 10.2 (2014 Apr-Jun): 177-85.

    Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 306.8 (2014 Apr 15): G670-6.

    All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
    Boyer JL
    The Journal of pharmacology and experimental therapeutics 349.1 (2014 Apr): 94-8.

    Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.
    Forbes SJ
    Hepatology (Baltimore, Md.) 60.5 (2014 Nov): 1727-40.

    Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Means AL
    Oncogene 33.7 (2014 Feb 13): 823-31.

    Cholestasis induces reversible accumulation of periplakin in mouse liver.
    Gonzalez FJ
    BMC gastroenterology 13. (2013 Jul 13): 116.

    Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Yeung RS
    Gastroenterology 144.5 (2013 May): 1055-65.

    The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
    Rustgi AK
    Genes and development 27.3 (2013 Feb 1): 288-300.

    FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.
    Miyajima A
    Genes and development 27.2 (2013 Jan 15): 169-81.

    Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
    di Magliano MP
    PloS one 7.12 (2012): e49707.

    Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.
    Leclercq IA
    Gastroenterology 143.6 (2012 Dec): 1564-1575.e7.

    A porcine model of familial adenomatous polyposis.
    Schnieke A
    Gastroenterology 143.5 (2012 Nov): 1173-1175.e7.

    Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
    Strazzabosco M
    Gastroenterology 141.4 (2011 Oct): 1498-508, 1508.e1-5.

    Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
    Korc M
    PloS one 6.11 (2011): e27725.

    Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
    Miyazaki J
    PloS one 7.10 (2012): e47536.

    GATA4 and GATA6 control mouse pancreas organogenesis.
    Rojas A
    The Journal of clinical investigation 122.10 (2012 Oct): 3504-15.

    EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
    Siveke JT
    Cancer cell 22.3 (2012 Sep 11): 304-17.

    Yes-associated protein regulates the hepatic response after bile duct ligation.
    Anders RA
    Hepatology (Baltimore, Md.) 56.3 (2012 Sep): 1097-107.

    MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.
    Siveke JT
    PloS one 7.6 (2012): e39424.

    Development and characterization of an organotypic model of Barrett's esophagus.
    Maley CC
    Journal of cellular physiology 227.6 (2012 Jun): 2654-9.

    A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
    Korc M
    Oncogene 31.20 (2012 May 17): 2535-44.

    Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.
    Boyer JL
    American journal of physiology. Gastrointestinal and liver physiology 302.9 (2012 May 1): G925-36.

    Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.
    Pasca di Magliano M
    The Journal of clinical investigation 122.2 (2012 Feb): 639-53.

    Secretin is not necessary for exocrine pancreatic development and growth in mice.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 301.5 (2011 Nov): G791-8.

    Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury.
    Leclercq I
    The American journal of pathology 179.4 (2011 Oct): 1839-50.

    Osteopontin upregulation in rotavirus-induced murine biliary atresia requires replicating virus but is not necessary for development of biliary atresia.
    Estes MK
    Virology 417.2 (2011 Sep 1): 281-92.

    Early requirement of Rac1 in a mouse model of pancreatic cancer.
    Siveke JT
    Gastroenterology 141.2 (2011 Aug): 719-30, 730.e1-7.

    PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
    DePinho RA
    Cancer discovery 1.2 (2011 Jul): 158-69.

    Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.
    Barbacid M
    Cancer cell 19.6 (2011 Jun 14): 728-39.

    Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice.
    Huppert SS
    Disease models and mechanisms 4.3 (2011 May): 359-67.

    Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.
    Omary MB
    Proceedings of the National Academy of Sciences of the United States of America 108.4 (2011 Jan 25): 1445-50.

    Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
    Bar-Sagi D
    Cancer cell 18.5 (2010 Nov 16): 448-58.

    Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis.
    Boyer JL
    Hepatology (Baltimore, Md.) 51.1 (2010 Jan): 181-90.

    Foxl1 promotes liver repair following cholestatic injury in mice.
    Greenbaum LE
    Laboratory investigation; a journal of technical methods and pathology 89.12 (2009 Dec): 1387-96.

    Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms.
    Copple BL
    Liver international : official journal of the International Association for the Study of the Liver 30.5 (2010 May): 669-82.

    Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
    Reisinger EC
    Tropical medicine and international health : TM and IH 14.11 (2009 Nov): 1418-25.

    E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
    Saur D
    Gastroenterology 137.1 (2009 Jul): 361-71, 371.e1-5.

    High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model.
    Gorden DL
    The American journal of pathology 175.1 (2009 Jul): 355-64.

    Foxa1 and Foxa2 regulate bile duct development in mice.
    Kaestner KH
    The Journal of clinical investigation 119.6 (2009 Jun): 1537-45.

    Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
    Trauner M
    Hepatology (Baltimore, Md.) 49.6 (2009 Jun): 1972-81.

    Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.
    Korc M
    Biochemical and biophysical research communications 382.3 (2009 May 8): 561-5.

    Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
    Leclercq IA
    Hepatology (Baltimore, Md.) 49.5 (2009 May): 1625-35.

    Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
    de Sauvage FJ
    Proceedings of the National Academy of Sciences of the United States of America 106.11 (2009 Mar 17): 4254-9.

    Cytoskeletal proteins in thymic epithelial cells of the Australian lungfish Neoceratodus forsteri.
    Joss J
    Journal of anatomy 214.1 (2009 Jan): 140-52.

    Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.
    Rustgi AK
    PloS one 3.10 (2008): e3534.

    Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice.
    Greenberg HB
    Journal of virology 82.15 (2008 Aug): 7578-90.

    Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.
    Matzuk MM
    Molecular and cellular biology 28.1 (2008 Jan): 248-57.

    Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.
    Omary MB
    Molecular biology of the cell 18.12 (2007 Dec): 4969-78.

    Intraovarian activins are required for female fertility.
    Matzuk MM
    Molecular endocrinology (Baltimore, Md.) 21.10 (2007 Oct): 2458-71.

    Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.
    Cho KR
    Cancer cell 11.4 (2007 Apr): 321-33.

    The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia.
    Korc M
    Proceedings of the National Academy of Sciences of the United States of America 104.11 (2007 Mar 13): 4437-42.

    Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
    Hebrok M
    Genes and development 20.22 (2006 Nov 15): 3161-73.

    In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas.
    Chen Y
    Proceedings of the National Academy of Sciences of the United States of America 103.6 (2006 Feb 7): 1858-63.

    Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
    Trauner M
    The American journal of pathology 168.2 (2006 Feb): 410-22.

    24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
    Trauner M
    Gastroenterology 130.2 (2006 Feb): 465-81.

    Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development.
    Jacob F
    Journal of embryology and experimental morphology 64. (1981 Aug): 45-60.

    Genetic Lineage Tracing of Biliary Epithelial Cells.
    Sancho-Bru P
    Methods in molecular biology (Clifton, N.J.) 1905. (2019): 45-57.

    TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma.
    Ikehara Y
    Scientific reports 9.1 (2019 Aug 2): 11247.

    Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
    Dong XC
    Biochimica et biophysica acta. Molecular basis of disease 1865.10 (2019 Oct 1): 2685-2693.

    Arid1a restrains Kras-dependent changes in acinar cell identity.
    Lowe SW
    eLife 7. (2018 Jul 17): .

    Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis.
    Fuster G
    Breast cancer research : BCR 20.1 (2018 Jul 4): 65.

    HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.
    Schwabe RF
    The Journal of clinical investigation 128.6 (2018 Jun 1): 2436-2451.

    Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.
    McNamara NA
    PloS one 12.9 (2017): e0184916.

    The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals.
    Bai H
    Laboratory investigation; a journal of technical methods and pathology 97.7 (2017 Jul): 843-853.

    Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
    Österreicher CH
    Oncotarget 7.52 (2016 Dec 27): 86985-86998.

    Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma.
    Gao ZH
    Oncotarget 7.47 (2016 Nov 22): 77838-77853.

    SOX2 regulates acinar cell development in the salivary gland.
    Knox SM
    eLife 6. (2017 Jun 17): .

    Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration.
    Zhou B
    The Journal of biological chemistry 292.21 (2017 May 26): 8594-8604.

    Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
    Kobayashi A
    Developmental cell 41.4 (2017 May 22): 349-365.e3.

    Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models.
    Dezső K
    PloS one 12.4 (2017): e0176518.

    Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.
    Charles RP
    Oncotarget 8.15 (2017 Apr 11): 24604-24620.

    FGF21 Is an Exocrine Pancreas Secretagogue.
    Mangelsdorf DJ
    Cell metabolism 25.2 (2017 Feb 7): 472-480.

    Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration.
    Zhou B
    Nature communications 7. (2016 Nov 18): 13369.

    LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
    Bardeesy N
    Nature 539.7629 (2016 Nov 17): 390-395.

    Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.
    van Grunsven LA
    PloS one 11.9 (2016): e0162286.

    The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.
    Wells RG
    Hepatology (Baltimore, Md.) 64.3 (2016 Sep): 880-93.

    Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.
    Miyazaki J
    PloS one 11.8 (2016): e0161190.

    K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds.
    Stepp MA
    Developmental dynamics : an official publication of the American Association of Anatomists 245.2 (2016 Feb): 132-43.

    Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
    Pikarsky E
    Nature immunology 16.12 (2015 Dec): 1235-44.

    Comparison of methods for the isolation of human breast epithelial and myoepithelial cells.
    Gascón P
    Frontiers in cell and developmental biology 3. (2015): 32.

    Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and β-cell regeneration in mice.
    Esni F
    Gastroenterology 147.5 (2014 Nov): 1106-18.e11.

    The biliary epithelium gives rise to liver progenitor cells.
    Sancho-Bru P
    Hepatology (Baltimore, Md.) 60.4 (2014 Oct): 1367-77.

    Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.
    Fuchs P
    PloS one 9.9 (2014): e108323.

    Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
    Knox SM
    Developmental cell 30.4 (2014 Aug 25): 449-62.

    Tannic acid label indicates abnormal cell development coinciding with regeneration of renal tubules.
    Denk L
    BMC clinical pathology 14. (2014): 34.

    Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors.
    LaBarge MA
    Cell reports 7.6 (2014 Jun 26): 1926-39.

    Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
    Machesky LM
    Gastroenterology 146.5 (2014 May): 1386-96.e1-17.

    MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
    Pasca di Magliano M
    Gastroenterology 146.3 (2014 Mar): 822-834.e7.

    Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver.
    Loomes KM
    PloS one 8.12 (2013): e84383.

    Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
    Korc M
    The Journal of clinical investigation 124.1 (2014 Jan): 338-52.

    Keratin 8 modulates β-cell stress responses and normoglycaemia.
    Toivola DM
    Journal of cell science 126.Pt 24 (2013 Dec 15): 5635-44.

    A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration.
    Tsai RY
    Hepatology (Baltimore, Md.) 58.6 (2013 Dec): 2176-87.

    Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy.
    Batra SK
    PloS one 8.11 (2013): e80580.

    Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
    Schwabe RF
    Nature communications 4. (2013): 2823.

    Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
    Philips MR
    The Journal of clinical investigation 123.11 (2013 Nov): 4681-94.

    Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
    di Magliano MP
    Cancer research 73.20 (2013 Oct 15): 6359-74.

    Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length.
    LaBarge MA
    Genome integrity 4.1 (2013 May 29): 4.

    Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.
    Guiot Y
    American journal of physiology. Endocrinology and metabolism 304.7 (2013 Apr 1): E711-23.

    Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells.
    Niemann H
    Stem cells and development 22.1 (2013 Jan 1): 124-35.

    Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine.
    Leiter AB
    Developmental biology 371.2 (2012 Nov 15): 156-69.

    Rotavirus infection of human cholangiocytes parallels the murine model of biliary atresia.
    Tiao G
    The Journal of surgical research 177.2 (2012 Oct): 275-81.

    c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro.
    Williams JA
    American journal of physiology. Gastrointestinal and liver physiology 302.12 (2012 Jun 15): G1381-96.

    Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia.
    Bar-Sagi D
    Cancer cell 21.6 (2012 Jun 12): 836-47.

    Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.
    Murray NR
    PloS one 7.2 (2012): e30509.

    Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.
    Omary MB
    The Journal of cell biology 195.2 (2011 Oct 17): 217-29.

    Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.
    Esni F
    Gastroenterology 141.4 (2011 Oct): 1451-62, 1462.e1-6.

    Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis.
    Wells RG
    Hepatology (Baltimore, Md.) 53.5 (2011 May): 1685-95.

    Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
    Diehl AM
    American journal of physiology. Gastrointestinal and liver physiology 300.2 (2011 Feb): G303-15.

    Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
    Iruela-Arispe ML
    Development (Cambridge, England) 137.23 (2010 Dec): 4061-72.

    Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation.
    Benedetti A
    Journal of hepatology 53.4 (2010 Oct): 663-70.

    Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice.
    Kisseleva T
    Gastroenterology 139.3 (2010 Sep): 987-98.

    Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.
    Omary MB
    Gastroenterology 138.4 (2010 Apr): 1607-17.

    Cytokeratin expression during mouse embryonic and early postnatal mammary gland development.
    Dai X
    Histochemistry and cell biology 133.2 (2010 Feb): 213-21.

    DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
    Pezzano M
    PloS one 5.2 (2010 Feb 8): e9062.

    Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.
    Navarro P
    Gastroenterology 136.4 (2009 Apr): 1379-90, e1-5.

    Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments.
    Bissell MJ
    Integrative biology : quantitative biosciences from nano to macro 1.1 (2009 Jan): 70-9.

    Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction.
    Dhouailly D
    Developmental dynamics : an official publication of the American Association of Anatomists 236.3 (2007 Mar): 755-68.

    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
    Omary MB
    Journal of cell science 117.Pt 9 (2004 Apr 1): 1709-19.

    Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.
    Jacob F
    Proceedings of the National Academy of Sciences of the United States of America 77.7 (1980 Jul): 4113-7.

    F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
    Dupont S
    Journal of hepatology 71.1 (2019 Jul): 130-142.

    Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.
    Labarge MA
    Cancer research 72.14 (2012 Jul 15): 3687-701.

    High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia.
    Lorens JB
    Cell reports 23.4 (2018 Apr 24): 1205-1219.

    Chondrocyte-like nested cells in the aged intervertebral disc are late-stage nucleus pulposus cells.
    Dahia CL
    Aging cell 18.5 (2019 Oct): e13006.

    Generation and characterisation of keratin 7 (K7) knockout mice.
    McLean WH
    PloS one 8.5 (2013): e64404.

    Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
    Omary MB
    The Journal of biological chemistry 286.3 (2011 Jan 21): 2273-84.

    Tumor-initiating function of nucleostemin-enriched mammary tumor cells.
    Tsai RY
    Cancer research 70.22 (2010 Nov 15): 9444-52.

    Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity.
    Omary MB
    Hepatology (Baltimore, Md.) 50.2 (2009 Aug): 546-54.

    Keratins modulate colonocyte electrolyte transport via protein mistargeting.
    Omary MB
    The Journal of cell biology 164.6 (2004 Mar 15): 911-21.

    Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
    Ostrowski MC
    Genes and development 30.17 (2016 Sep 1): 1943-55.

    Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.
    Karin M
    Cell 162.4 (2015 Aug 13): 766-79.

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